Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5192 proteins Structure: AlphaFold

Scoring formula None

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Structure: AlphaFold ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
101 KP13_04379 hypothetical protein AlphaFold + ColabFold – – 0.989 No Hit 0.0% —
102 KP13_03903 Putrescine importer puuP AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +25 total
0.989 Hit 25.0% 1.90e-09
103 KP13_03722 hypothetical protein AlphaFold + ColabFold – – 0.989 No Hit 0.0% —
104 KP13_03286 putative transmembrane protein AlphaFold + ColabFold – – 0.989 No Hit 0.0% —
105 KP13_01723 Lysophospholipase L2 pldB AlphaFold + ColabFold
3.1.1.5
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0004622Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H+ + sn-glycerol 3-phosphocholine. GO:0006629The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
0.989 No Hit 0.0% —
106 KP13_01606 Inner membrane protein AlphaFold + ColabFold – – 0.989 No Hit 0.0% —
107 KP13_00276 Cellulose synthase catalytic subunit acsA AlphaFold + ColabFold
2.4.1.12
GO:0035438Binding to cyclic-di-GMP, cyclic dimeric guanosine monophosphate. GO:0030244The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. GO:0016759Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1). +47 total
0.989 No Hit 0.0% —
108 KP13_00236 Xylose transport system permease protein xylH xylH AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +14 total
0.989 No Hit 0.0% —
109 KP13_00029 Glucosamine--fructose-6-phosphate aminotransferase isomerizing glmS AlphaFold + ColabFold
2.6.1.16
GO:1901135The chemical reactions and pathways involving carbohydrate derivative. GO:0097367Binding to a carbohydrate derivative. GO:0004360Catalysis of the reaction: D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate. +710 total
0.989 Hit 40.9% 4.81e-94
110 KP13_32345 SbmA sbmA AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:1904680Enables the transfer of a peptide from one side of a membrane to the other. +25 total
0.988 No Hit 0.0% —
111 KP13_05381 Inner membrane protein AlphaFold + ColabFold – – 0.988 No Hit 0.0% —
112 KP13_04839 putative inner membrane transporter AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.988 No Hit 0.0% —
113 KP13_04579 Catalase-peroxidase bifunctional enzyme katG AlphaFold + ColabFold
1.11.1.21
GO:0004096Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O. GO:0020037Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. GO:0004601Catalysis of the reaction: a reduced substrate + ROOH = an oxidized substrate + ROH + H2O. +58 total
0.988 No Hit 0.0% —
114 KP13_04529 Formate dehydrogenase, nitrate-inducible, cytochrome b556(fdn) subunit fdnI AlphaFold + ColabFold –
GO:0008863Catalysis of the reaction: formate + NAD+ = CO2 + NADH. GO:0009055A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +811 total
0.988 No Hit 0.0% —
115 KP13_04333 putative Inner membrane protein AlphaFold + ColabFold – – 0.988 No Hit 0.0% —
116 KP13_04121 hypothetical protein AlphaFold + ColabFold – – 0.988 No Hit 0.0% —
117 KP13_03864 Paraquat-inducible protein A pqiA AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.988 No Hit 0.0% —
118 KP13_03538 Inner membrane protein AlphaFold + ColabFold – – 0.988 No Hit 0.0% —
119 KP13_01731 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE ubiE AlphaFold + ColabFold
2.1.1.163 2.1.1.201
GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0008425Catalysis of the reaction: a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+. GO:0043770Catalysis of the reaction: a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H+ + S-adenosyl-L-homocysteine. Reaction substrates can have varying polyprenyl side chain length. +36 total
0.988 Hit 56.0% 9.14e-11
120 KP13_00518 putative mscS family protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.988 No Hit 0.0% —
121 KP13_00337 TMEM86 family protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
0.988 No Hit 0.0% —
122 KP13_04170 Nicotinate phosphoribosyltransferase pncB AlphaFold + ColabFold
6.3.4.21
GO:0004516Catalysis of the reaction: nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate. GO:0009435The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD+), a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions. NAD+ is derived from various sources including vitamin B3. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.987 No Hit 0.0% —
123 KP13_03190 Putative osmoprotectant uptake system permease protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.987 No Hit 0.0% —
124 KP13_01427 Ribosomal RNA methyltransferase grm AlphaFold + ColabFold
2.1.1.179
GO:0046677Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. GO:0008649Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule. The methyl group can be transfered to the nucleobase or to the ribose group of the nucleoside. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
0.987 No Hit 0.0% —
125 KP13_00334 putative integral membrane protein AlphaFold + ColabFold –
GO:1990397OBSOLETE. Any process which produces queuosine from derivatives of it, without de novo synthesis.
0.987 No Hit 0.0% —
Page of 208 · 5192 total proteins