Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
5842 / 5842 proteins

Scoring formula None

Sorted by Human E-value (ascending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
2226 KP13_01434 transposase for insertion sequence-like element IS431mec tnp AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
2227 KP13_01435 Integrase core subunit rve AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.57 No Hit 0.0% —
2228 KP13_01437 putative mercuric resistance protein merE AlphaFold + ColabFold –
GO:0015097Enables the transfer of mercury (Hg2+) ions from one side of a membrane to the other. GO:0015694The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.861 No Hit 0.0% —
2229 KP13_01442 Mercuric transport protein merT AlphaFold + ColabFold –
GO:0015097Enables the transfer of mercury (Hg2+) ions from one side of a membrane to the other. GO:0015694The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +25 total
No map 0.916 No Hit 0.0% —
2230 KP13_01443 Mercuric resistance operon regulatory protein merR AlphaFold + ColabFold –
GO:0045340Binding to a mercury ion (Hg2+). GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +25 total
No map 0.638 No Hit 0.0% —
2231 KP13_01444 transposase for insertion sequence element IS1328 AlphaFold + ColabFold –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.783 No Hit 0.0% —
2232 KP13_01445 hypothetical protein ColabFold – – No map 0.409 No Hit 0.0% —
2233 KP13_01446 hypothetical protein AlphaFold + ColabFold – – No map 0.724 No Hit 0.0% —
2234 KP13_01447 hypothetical protein ColabFold – – No map 0.973 No Hit 0.0% —
2235 KP13_01448 Chorismate mutase aroH AlphaFold + ColabFold
5.4.99.5
GO:0046417The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid. GO:0004106Catalysis of the reaction: chorismate = prephenate. GO:0009697The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
No map 0.525 No Hit 0.0% —
2236 KP13_01450 hypothetical protein ColabFold – – No map 0.532 No Hit 0.0% —
2237 KP13_01451 hypothetical protein AlphaFold + ColabFold – – No map 0.61 No Hit 0.0% —
2238 KP13_01452 hypothetical protein AlphaFold + ColabFold – – No map 0.463 No Hit 0.0% —
2239 KP13_01453 hypothetical protein AlphaFold + ColabFold – – No map 0.196 No Hit 0.0% —
2240 KP13_01454 Replication protein repA repA AlphaFold + ColabFold –
GO:0003887Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. GO:0006270The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding.
No map 0.604 No Hit 0.0% —
2241 KP13_01455 hypothetical protein ColabFold – – No map 0.906 No Hit 0.0% —
2242 KP13_01457 Cation transport regulator chaB chaB AlphaFold + ColabFold – – No map 0.152 No Hit 0.0% —
2243 KP13_01458 Calcium/proton antiporter chaA AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +25 total
No map 0.775 No Hit 0.0% —
2244 KP13_01459 2-dehydro-3-deoxyphosphooctonate aldolase kdsA AlphaFold + ColabFold
2.5.1.55
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0009058A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. GO:0008676Catalysis of the reaction: D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H+ + phosphate. +14 total
No map 0.305 No Hit 0.0% —
2245 KP13_01460 Protein sirB1 sirB1 AlphaFold + ColabFold – – No map 0.377 No Hit 0.0% —
2246 KP13_01461 Protein sirB2 sirB2 AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.998 No Hit 0.0% —
2247 KP13_01464 Glutamyl-tRNA reductase hemA AlphaFold + ColabFold
1.2.1.70
GO:0008883Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H+ + NADPH. GO:0050661Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. GO:0033014The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. +14 total
No map 0.515 No Hit 0.0% —
2248 KP13_01465 Outer-membrane lipoprotein lolB lolB AlphaFold + ColabFold –
GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0015031The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0044874A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.
No map 0.662 No Hit 0.0% —
2249 KP13_01466 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE Experimental + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016114The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. GO:0050515Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H+.
No map 0.628 No Hit 0.0% —
2250 KP13_01469 MerR family transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
No map 0.991 No Hit 0.0% —
Page of 234 · 5842 total proteins