Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
5842 / 5842 proteins

Scoring formula None

Sorted by Human identity (%) (ascending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
376 KP13_00601 Alpha-galactosidase rafA AlphaFold + ColabFold
3.2.1.22
GO:0004557Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. GO:0016052The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. +14 total
0.199 No Hit 0.0% —
377 KP13_00602 HTH-type transcriptional regulator rafR rafR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +14 total
0.733 No Hit 0.0% —
378 KP13_00603 putative HTH-type transcriptional regulator AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
0.28 No Hit 0.0% —
379 KP13_00604 AzlC family protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:1903785The directed movement of L-valine across a membrane.
0.579 No Hit 0.0% —
380 KP13_00605 hypothetical protein AlphaFold + ColabFold – – 0.096 No Hit 0.0% —
381 KP13_00606 hypothetical protein AlphaFold + ColabFold – – 0.003 No Hit 0.0% —
382 KP13_00607 Protein fdhD fdhD AlphaFold + ColabFold –
GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0016783Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +25 total
0.23 No Hit 0.0% —
383 KP13_00611 Formate dehydrogenase, cytochrome b556(fdo) subunit fdoI AlphaFold + ColabFold –
GO:0008863Catalysis of the reaction: formate + NAD+ = CO2 + NADH. GO:0009055A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +811 total
0.962 No Hit 0.0% —
384 KP13_00612 Protein fdhE fdhE AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0008199Binding to a ferric iron ion, Fe(III). +14 total
0.486 No Hit 0.0% —
385 KP13_00613 PilT domain-containing protein AlphaFold + ColabFold –
GO:0004540Catalysis of the cleavage of phosphodiester bonds in chains of RNA.
0.254 No Hit 0.0% —
386 KP13_00614 hypothetical protein Experimental + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
0.333 No Hit 0.0% —
387 KP13_00616 GCN5-related N-acetyltransferase AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). GO:0006048The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0004343Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H+. +25 total
0.22 No Hit 0.0% —
388 KP13_00618 putative membrane protein AlphaFold + ColabFold – – 0.906 No Hit 0.0% —
389 KP13_00621 hypothetical protein ColabFold – – 0.899 No Hit 0.0% —
390 KP13_00623 Nitrogen regulation protein ntrB ntrB AlphaFold + ColabFold –
GO:0016310The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0016772Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). +25 total
0.823 No Hit 0.0% —
391 KP13_00626 hypothetical protein AlphaFold + ColabFold –
GO:0005096Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. GO:0042254A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
0.653 No Hit 0.0% —
392 KP13_00627 hypothetical protein ColabFold – – 0.819 No Hit 0.0% —
393 KP13_00630 hypothetical protein ColabFold – – 0.8 No Hit 0.0% —
394 KP13_00631 putative acyltransferase ColabFold –
GO:0016746Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
0.973 No Hit 0.0% —
395 KP13_00633 Protein rdoA rdoA AlphaFold + ColabFold
2.7.11.1
GO:0006468The process of introducing a phosphate group on to a protein. GO:0004674Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +36 total
0.649 No Hit 0.0% —
396 KP13_00634 hypothetical protein AlphaFold + ColabFold – – 0.422 No Hit 0.0% —
397 KP13_00635 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA AlphaFold + ColabFold –
GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0006777The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
0.5 No Hit 0.0% —
398 KP13_00636 Molybdopterin-guanine dinucleotide biosynthesis protein B mobB AlphaFold + ColabFold –
GO:0005525Binding to GTP, guanosine triphosphate. GO:0006777The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
0.437 No Hit 0.0% —
399 KP13_00637 putative acyltransferase AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). GO:0015940The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. GO:0031638The proteolytic processing of an inactive enzyme to an active form.
0.805 No Hit 0.0% —
400 KP13_00639 hypothetical protein AlphaFold + ColabFold – – 0.587 No Hit 0.0% —
Page of 234 · 5842 total proteins