Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4751 KP13_05123 hypothetical protein AlphaFold + ColabFold – – 0.007 No Hit 0.0% —
4752 KP13_05124 hypothetical protein AlphaFold + ColabFold – – 0.446 No Hit 0.0% —
4753 KP13_05125 hypothetical protein AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.808 No Hit 0.0% —
4754 KP13_05127 hypothetical protein AlphaFold + ColabFold – – 0.412 No Hit 0.0% —
4755 KP13_05128 LysR family transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. +14 total
0.717 No Hit 0.0% —
4756 KP13_05129 hypothetical protein ColabFold – – 0.657 No Hit 0.0% —
4757 KP13_05130 type VI secretion ATPase, ClpV1 family AlphaFold + ColabFold – – 0.826 No Hit 0.0% —
4758 KP13_05131 hypothetical protein AlphaFold + ColabFold – – 0.771 No Hit 0.0% —
4759 KP13_05132 hypothetical protein ColabFold – – 0.753 No Hit 0.0% —
4760 KP13_05133 decarboxylase family protein AlphaFold + ColabFold
3.2.2.n1
GO:0009691The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +14 total
0.365 No Hit 0.0% —
4761 KP13_05134 Acid shock protein AlphaFold + ColabFold –
GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
0.1 No Hit 0.0% —
4762 KP13_05136 Riboflavin synthase alpha chain ribE AlphaFold + ColabFold
2.5.1.9
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0004746Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ = 5-amino-6-(D-ribitylamino)uracil + riboflavin. GO:0009231The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
0.27 No Hit 0.0% —
4763 KP13_05137 Cyclopropane-fatty-acyl-phospholipid synthase AlphaFold + ColabFold –
GO:0008610The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0032259The process in which a methyl group is covalently attached to a molecule.
1 No Hit 0.0% —
4764 KP13_05138 Inner membrane transport protein AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:1990961A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +36 total
0.77 No Hit 0.0% —
4765 KP13_05139 HTH-type transcriptional repressor purR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +36 total
0.774 No Hit 0.0% —
4766 KP13_05140 hypothetical protein ColabFold – – 0.715 No Hit 0.0% —
4767 KP13_05142 Inner membrane transport protein AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.986 No Hit 0.0% —
4768 KP13_05144 hypothetical protein AlphaFold + ColabFold –
GO:0008234Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
0.275 No Hit 0.0% —
4769 KP13_05145 hypothetical protein AlphaFold + ColabFold – – 0.038 No Hit 0.0% —
4770 KP13_05148 Ribonuclease T rnt AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0004540Catalysis of the cleavage of phosphodiester bonds in chains of RNA. GO:0006396Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
0.606 No Hit 0.0% —
4771 KP13_05150 N-ethylmaleimide reductase nemA Experimental + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0010181Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +14 total
0.915 No Hit 0.0% —
4772 KP13_05151 HTH-type transcriptional repressor nemR nemR AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.492 No Hit 0.0% —
4773 KP13_05152 hypothetical protein AlphaFold + ColabFold – – 0.151 No Hit 0.0% —
4774 KP13_05155 putative transporter AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.948 No Hit 0.0% —
4775 KP13_05156 HlyD-family protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.075 No Hit 0.0% —
Page of 234 · 5842 total proteins