Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5192 proteins Structure: AlphaFold

Scoring formula None

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Structure: AlphaFold ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5151 KP13_32212 Iron-binding protein iscA iscA AlphaFold + ColabFold –
GO:0016226The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. GO:0051536Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.014 Hit 54.8% 7.79e-07
5152 KP13_05328 hypothetical protein AlphaFold + ColabFold – – 0.014 No Hit 0.0% —
5153 KP13_04498 putative GST-like protein AlphaFold + ColabFold – – 0.014 No Hit 0.0% —
5154 KP13_00906 hypothetical protein AlphaFold + ColabFold – – 0.014 No Hit 0.0% —
5155 KP13_01337 hypothetical protein AlphaFold + ColabFold –
GO:0006302The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0000731Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.
0.013 No Hit 0.0% —
5156 KP13_03803 putative glycosyltransferase family 2 in cps region AlphaFold + ColabFold –
GO:0016757Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
0.012 No Hit 0.0% —
5157 KP13_01022 Protein dedD dedD AlphaFold + ColabFold –
GO:0042834Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls. GO:0030428A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:0032506A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells). +25 total
0.012 No Hit 0.0% —
5158 KP13_05215 hypothetical protein AlphaFold + ColabFold – – 0.009 No Hit 0.0% —
5159 KP13_05123 hypothetical protein AlphaFold + ColabFold – – 0.007 No Hit 0.0% —
5160 KP13_03389 putative oxidoreductase AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0016614Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0046872Binding to a metal ion.
0.007 No Hit 0.0% —
5161 KP13_01737 Deoxyribonuclease tatD tatD AlphaFold + ColabFold
3.1.11.- 3.1.13.-
GO:0016788Catalysis of the hydrolysis of any ester bond. GO:0008408Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.007 Hit 36.4% 3.42e-14
5162 KP13_06826 hypothetical protein AlphaFold + ColabFold – – 0.006 No Hit 0.0% —
5163 KP13_05544 Cell envelope integrity inner membrane protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0019534Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GO:0043213The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.
0.006 No Hit 0.0% —
5164 KP13_04723 hypothetical protein AlphaFold + ColabFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
0.005 No Hit 0.0% —
5165 KP13_02520 Lipoprotein nlpD nlpD AlphaFold + ColabFold –
GO:0032153The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles. GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +25 total
0.005 No Hit 0.0% —
5166 KP13_02308 putative propanediol utilization protein AlphaFold + ColabFold –
GO:0031469An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
0.005 No Hit 0.0% —
5167 KP13_02302 Propanediol utilization protein pduU pduU AlphaFold + ColabFold –
GO:0031469An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
0.005 No Hit 0.0% —
5168 KP13_02257 hypothetical protein AlphaFold + ColabFold – – 0.005 No Hit 0.0% —
5169 KP13_02209 hypothetical protein AlphaFold + ColabFold – – 0.005 No Hit 0.0% —
5170 KP13_03552 Phosphocarrier protein HPr ptsH AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0009401The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
0.003 No Hit 0.0% —
5171 KP13_00606 hypothetical protein AlphaFold + ColabFold – – 0.003 No Hit 0.0% —
5172 KP13_05008 Putative selenoprotein AlphaFold + ColabFold – – 0.002 No Hit 0.0% —
5173 KP13_32137 hypothetical protein AlphaFold + ColabFold – – 0.001 No Hit 0.0% —
5174 KP13_06036 hypothetical protein AlphaFold + ColabFold – – 0.001 No Hit 0.0% —
5175 KP13_05277 hypothetical protein AlphaFold + ColabFold – – 0.001 No Hit 0.0% —
Page of 208 · 5192 total proteins