Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5776 KP13_32181 HTH-type transcriptional repressor NsrR nsrR AlphaFold + ColabFold –
GO:0045892Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. +36 total
0.227 No Hit 0.0% —
5777 KP13_32182 Protein hfq hfq AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003723Binding to an RNA molecule or a portion thereof. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.221 No Hit 0.0% —
5778 KP13_32185 hypothetical protein AlphaFold + ColabFold – – 0.113 No Hit 0.0% —
5779 KP13_32187 Proline porter II AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +25 total
0.514 No Hit 0.0% —
5780 KP13_32188 Two-component regulatory system response regulator protein AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +47 total
0.527 No Hit 0.0% —
5781 KP13_32189 inner membrane protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0015205Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other. +36 total
0.955 No Hit 0.0% —
5782 KP13_32192 RmlC-type domain-containing protein AlphaFold + ColabFold – – 0.584 No Hit 0.0% —
5783 KP13_32194 hypothetical protein AlphaFold + ColabFold – – 0.948 No Hit 0.0% —
5784 KP13_32195 hypothetical protein ColabFold – – 0.797 No Hit 0.0% —
5785 KP13_32196 HTH-type transcriptional regulator MetR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +25 total
0.3 No Hit 0.0% —
5786 KP13_32199 hypothetical protein AlphaFold + ColabFold – – 0.147 No Hit 0.0% —
5787 KP13_32201 hypothetical protein ColabFold – – 0.68 No Hit 0.0% —
5788 KP13_32203 hypothetical protein AlphaFold + ColabFold – – 0.321 No Hit 0.0% —
5789 KP13_32204 hypothetical protein AlphaFold + ColabFold – – 0.828 No Hit 0.0% —
5790 KP13_32205 multidrug resistance protein mdtL AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.78 No Hit 0.0% —
5791 KP13_32206 membrane protein insertion efficiency factor AlphaFold + ColabFold – – 0.978 No Hit 0.0% —
5792 KP13_32207 hypothetical protein AlphaFold + ColabFold – – 0.329 No Hit 0.0% —
5793 KP13_32209 hypothetical protein ColabFold – – 0.583 No Hit 0.0% —
5794 KP13_32211 transcription elongation factor GreB AlphaFold + ColabFold –
GO:0032784Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. GO:0070063Binding to an RNA polymerase molecule or complex. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +25 total
0.419 No Hit 0.0% —
5795 KP13_32214 putative lipoprotein AlphaFold + ColabFold – – 0.568 No Hit 0.0% —
5796 KP13_32218 Transcription termination factor rho rho AlphaFold + ColabFold
3.6.4.-
GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0003676Binding to a nucleic acid. GO:0008186Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. +69 total
0.332 No Hit 0.0% —
5797 KP13_32220 Osmotically-inducible protein Y osmY AlphaFold + ColabFold –
GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
0.112 No Hit 0.0% —
5798 KP13_32221 D-aminoacylase dan Experimental + ColabFold –
GO:0016811Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. GO:0016810Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
0.494 No Hit 0.0% —
5799 KP13_32222 Transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.584 No Hit 0.0% —
5800 KP13_32230 Formate dehydrogenase H ColabFold –
GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0008863Catalysis of the reaction: formate + NAD+ = CO2 + NADH. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. +710 total
0.855 No Hit 0.0% —
Page of 234 · 5842 total proteins