Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
51 KP13_05004 sirA domain-containing protein AlphaFold + ColabFold – – 0.019 No Hit 0.0% —
52 KP13_05417 putative transposase InsK for insertion sequence element IS150 AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.019 No Hit 0.0% —
53 KP13_06831 putative transposase InsK for insertion sequence element IS150 AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.019 No Hit 0.0% —
54 KP13_31597 putative transposase InsK for insertion sequence element IS150 AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.019 No Hit 0.0% —
55 KP13_31884 putative transposase InsK for insertion sequence element IS150 AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.019 No Hit 0.0% —
56 KP13_32048 hypothetical protein ColabFold – – 0.019 Hit 62.2% 4.80e-08
57 KP13_04436 hypothetical protein AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0046872Binding to a metal ion. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +14 total
0.02 No Hit 0.0% —
58 KP13_04832 hypothetical protein AlphaFold + ColabFold –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.02 No Hit 0.0% —
59 KP13_02459 putative fimbrial protein AlphaFold + ColabFold –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.
0.021 No Hit 0.0% —
60 KP13_04408 Elongation factor P-like protein AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0003746Functions in chain elongation during polypeptide synthesis at the ribosome. GO:0043043The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. +25 total
0.021 No Hit 0.0% —
61 KP13_31612 Peptide methionine sulfoxide reductase msrA msrA AlphaFold + ColabFold
1.8.4.11
GO:0008113Catalysis of the reaction: L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0033744Catalysis of the reaction: [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol. +14 total
0.021 Hit 70.7% 3.01e-41
62 KP13_02478 N-acetyltransferase AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.022 No Hit 0.0% —
63 KP13_04518 Muconolactone Delta-isomerase catC AlphaFold + ColabFold
5.3.3.4
GO:0006725OBSOLETE. The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. GO:0016159Catalysis of the reaction: (S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate. GO:0042952A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.
0.022 No Hit 0.0% —
64 KP13_03911 hypothetical protein ColabFold – – 0.023 No Hit 0.0% —
65 KP13_32389 hypothetical protein ColabFold – – 0.023 No Hit 0.0% —
66 KP13_04531 hypothetical protein AlphaFold + ColabFold – – 0.025 No Hit 0.0% —
67 KP13_04576 hypothetical protein ColabFold – – 0.025 No Hit 0.0% —
68 KP13_31889 Cold shock-like protein CspE cspE AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
0.026 Hit 60.0% 6.40e-07
69 KP13_32400 hypothetical protein AlphaFold + ColabFold – – 0.026 No Hit 0.0% —
70 KP13_01348 UDP-N-acetylenolpyruvoylglucosamine reductase murB AlphaFold + ColabFold
1.3.1.98
GO:0071949Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0050660Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. GO:0008762Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+. +58 total
0.027 No Hit 0.0% —
71 KP13_02193 hypothetical protein AlphaFold + ColabFold – – 0.027 No Hit 0.0% —
72 KP13_31876 hypothetical protein ColabFold – – 0.028 No Hit 0.0% —
73 KP13_04566 hypothetical protein AlphaFold + ColabFold – – 0.029 No Hit 0.0% —
74 KP13_32004 biofilm-dependent modulation domain-containing protein AlphaFold + ColabFold –
GO:0071468Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
0.029 No Hit 0.0% —
75 KP13_00781 Peptide deformylase def AlphaFold + ColabFold –
GO:0042586Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.
0.03 Hit 32.3% 2.95e-17
Page of 234 · 5842 total proteins