Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
126 KP13_05297 hypothetical protein AlphaFold + ColabFold – – 0.048 No Hit 0.0% —
127 KP13_02850 PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM dhaM AlphaFold + ColabFold
2.7.1.121
GO:0047324Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate. GO:0016310The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. GO:0016772Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). +36 total
0.049 No Hit 0.0% —
128 KP13_04060 putative transposase ColabFold –
GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.049 No Hit 0.0% —
129 KP13_05185 hypothetical protein AlphaFold + ColabFold – – 0.049 No Hit 0.0% —
130 KP13_00201 ADP-heptose--LPS heptosyltransferase 2 rfaF AlphaFold + ColabFold
2.4.99.24
GO:0009103The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. GO:0016757Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.05 No Hit 0.0% —
131 KP13_05567 Aldo/keto reductase family AlphaFold + ColabFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
0.05 Hit 37.3% 6.21e-06
132 KP13_00262 hypothetical protein AlphaFold + ColabFold – – 0.051 No Hit 0.0% —
133 KP13_05143 Superoxide dismutase Fe sodB AlphaFold + ColabFold
1.15.1.1
GO:0004784Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + H2O2. GO:0006801The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. GO:0046872Binding to a metal ion. +25 total
0.051 Hit 58.3% 2.27e-07
134 KP13_06638 hypothetical protein AlphaFold + ColabFold – – 0.051 No Hit 0.0% —
135 KP13_01394 Protein pemK pemK AlphaFold + ColabFold
3.1.-.-
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0004521Catalysis of the cleavage of ester linkages within ribonucleic acid by creating internal breaks. +25 total
0.053 No Hit 0.0% —
136 KP13_02682 hypothetical protein AlphaFold + ColabFold – – 0.054 No Hit 0.0% —
137 KP13_02645 putative ferredoxin-like protein AlphaFold + ColabFold –
GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0051536Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.
0.055 No Hit 0.0% —
138 KP13_02764 hypothetical protein AlphaFold + ColabFold – – 0.055 No Hit 0.0% —
139 KP13_03537 Acetyltransferase AlphaFold + ColabFold
2.3.1.-
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.055 Hit 35.5% 1.57e-07
140 KP13_05416 hypothetical protein AlphaFold + ColabFold – – 0.055 No Hit 0.0% —
141 KP13_05556 LysM domain/BON superfamily protein AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
0.055 No Hit 0.0% —
142 KP13_02801 3,4-dihydroxy-2-butanone 4-phosphate synthase ribB AlphaFold + ColabFold –
GO:0008686Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H+. GO:0009231The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
0.056 No Hit 0.0% —
143 KP13_03863 ABC transporter ATP-binding protein uup uup AlphaFold + ColabFold
3.6.1.-
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0006281The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. +36 total
0.056 Hit 36.5% 1.00e-14
144 KP13_32367 hypothetical protein AlphaFold + ColabFold – – 0.056 No Hit 0.0% —
145 KP13_01070 hypothetical protein AlphaFold + ColabFold – – 0.057 No Hit 0.0% —
146 KP13_05300 hypothetical protein AlphaFold + ColabFold – – 0.057 No Hit 0.0% —
147 KP13_31535 putative transposase ColabFold – – 0.057 No Hit 0.0% —
148 KP13_03175 Rossmann-like alpha/beta/alpha sandwich fold domain-containing protein ColabFold – – 0.058 No Hit 0.0% —
149 KP13_05514 amino acid ABC transporter, ATP-binding protein AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0003333The process in which an amino acid is transported across a membrane. +25 total
0.058 Hit 61.1% 1.27e-06
150 KP13_06798 hypothetical protein ColabFold – – 0.058 No Hit 0.0% —
Page of 234 · 5842 total proteins