Proteins

Genome: NZ_AP023069.1

Description: Neisseria gonorrhoeae strain TUM19854 chromosome, complete genome

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18 proteins Structure: ColabFold

Scoring formula None

Sorted by Druggability (descending)

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Structure: ColabFold ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 HT085_RS00355 isoleucine--tRNA ligase ileS ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0002161The hydrolysis of an incorrectly aminoacylated tRNA.
No pocket Hit — —
2 HT085_RS00360 hypothetical protein ColabFold – – No pocket No Hit — —
3 HT085_RS00180 hypothetical protein ColabFold – – No pocket No Hit — —
4 HT085_RS00220 50S ribosomal protein L11 methyltransferase prmA ColabFold – – No pocket Hit — —
5 HT085_RS00160 factor H-binding protein ColabFold – – No pocket No Hit — —
6 HT085_RS00120 helix-turn-helix transcriptional regulator ColabFold –
GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
No pocket No Hit — —
7 HT085_RS00060 helix-turn-helix domain-containing protein ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No pocket No Hit — —
8 HT085_RS00150 ribosomal protein S18-alanine N-acetyltransferase rimI ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
No pocket No Hit — —
9 HT085_RS00340 hypothetical protein ColabFold – – No pocket No Hit — —
10 HT085_RS00245 carbamoyl-phosphate synthase large subunit carB ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0046872Binding to a metal ion.
No pocket Hit — —
11 HT085_RS00375 4-hydroxy-3-methylbut-2-enyl diphosphate reductase ispH ColabFold –
GO:0019288The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate. GO:0046872Binding to a metal ion.
No pocket No Hit — —
12 HT085_RS00105 TonB-dependent iron piracy receptor TdfF tdfF ColabFold – – No pocket No Hit — —
13 HT085_RS11595 hypothetical protein ColabFold – – No pocket No Hit — —
14 HT085_RS00270 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit carA ColabFold –
GO:0006207The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
No pocket Hit — —
15 HT085_RS00275 PilC family type IV pilus tip adhesin pilC ColabFold – – No pocket No Hit — —
16 HT085_RS00350 bifunctional riboflavin kinase/FAD synthetase ribF ColabFold – – No pocket Hit — —
17 HT085_RS00345 opacity family porin ColabFold – – No pocket No Hit — —
18 HT085_RS00365 opacity family porin ColabFold – – No pocket No Hit — —
Page 1 of 1 · 18 total proteins