KEGG:map00670

One carbon pool by folate

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 15
Proteins 14
Metabolites 39
Chokepoints 2

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 10 shared KEGG Glycine, serine and threonine metabolism 6 shared KEGG Glyoxylate and dicarboxylate metabolism 5 shared KEGG Purine metabolism 4 shared KEGG Pantothenate and CoA biosynthesis 3 shared KEGG Biosynthesis of various nucleotide sugars 2 shared KEGG Pyrimidine metabolism 2 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

1.5.1.20-RXN

EC 1.5.1.20 · R07168 · 1.5.1.20-RXN · reversible

NAD(P)+ a 5-methyltetrahydrofolate
⇌
NAD(P)H a 5,10-methylenetetrahydrofolate H+
VK055_3237

AICARTRANSFORM-RXN

EC 2.1.2.3 · R04560 · AICARTRANSFORM-RXN · not reversible

both
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide an N10-formyltetrahydrofolate
→
5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide a tetrahydrofolate
VK055_3086

BADH-RXN

EC 1.2.1.8 · R02565 · BADH-RXN · not reversible

betaine aldehyde H2O NAD+
→
glycine betaine H+ NADH
VK055_1952

CHD-RXN

EC 1.1.99.1 · R01025 · CHD-RXN · reversible

an oxidized electron carrier choline
⇌
a reduced two electron carrier betaine aldehyde
VK055_1953

FORMATETHFLIG-RXN

EC 6.3.4.3 · R00943 · FORMATETHFLIG-RXN · reversible

a tetrahydrofolate formate ATP
⇌
an N10-formyltetrahydrofolate ADP phosphate
VK055_0080

GART-RXN

EC 2.1.2.2 · R04325 · GART-RXN · not reversible

N1-(5-phospho-beta-D-ribosyl)glycinamide an N10-formyltetrahydrofolate
→
N2-formyl-N1-(5-phospho-beta-D-ribosyl)glycinamide a tetrahydrofolate H+
VK055_4685

GCVMULTI-RXN

EC 1.4.1.27 · R01221 · GCVMULTI-RXN · reversible

a tetrahydrofolate glycine NAD+
⇌
a 5,10-methylenetetrahydrofolate CO2 NADH ammonium
VK055_4143

GCVT-RXN

EC 2.1.2.10 · R04125 · GCVT-RXN · reversible

a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine a tetrahydrofolate
⇌
a 5,10-methylenetetrahydrofolate a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine ammonium
VK055_4142 VK055_4143

GLYOHMETRANS-RXN

EC 2.1.2.1 · R00945 · GLYOHMETRANS-RXN · reversible

a 5,10-methylenetetrahydrofolate glycine H2O
⇌
L-serine a tetrahydrofolate
VK055_4625

METHYLENETHFDEHYDROG-NADP-RXN

EC 1.5.1.5 · R01220 · METHYLENETHFDEHYDROG-NADP-RXN · reversible

a 5,10-methylenetetrahydrofolate NADP+
⇌
a 5,10-methenyltetrahydrofolate NADPH
No mapped protein