Proteins

Genome: KpATCC43816

Description: Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

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5081 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3726 VK055_5168 hypothetical protein AlphaFold + ColabFold – – 0.352 No Hit 0.0% —
3727 VK055_4637 tRNA:Cm32/Um32 methyltransferase AlphaFold + ColabFold
2.1.1.200
GO:0006396Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. GO:0008173Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule. GO:0003723Binding to an RNA molecule or a portion thereof. +47 total
0.352 No Hit 0.0% —
3728 VK055_4545 bacterial extracellular solute-binding, 3 familyprotein AlphaFold + ColabFold – – 0.352 No Hit 0.0% —
3729 VK055_4339 cobalt transport family protein cbiN AlphaFold + ColabFold –
GO:0006824The directed movement of cobalt (Co2+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015087Enables the transfer of cobalt (Co2+) ions from one side of a membrane to the other. +25 total
0.352 No Hit 0.0% —
3730 VK055_3678 hypothetical protein AlphaFold + ColabFold – – 0.352 No Hit 0.0% —
3731 VK055_3660 ugpC ugpC AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0140359Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. GO:0008643The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. +47 total
0.352 Hit 51.3% 6.41e-06
3732 VK055_2994 fimbrial family protein AlphaFold + ColabFold –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
0.352 No Hit 0.0% —
3733 VK055_2603 DNA polymerase III, psi subunit holD AlphaFold + ColabFold –
GO:0003887Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. GO:0008408Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. GO:0006260The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
0.352 No Hit 0.0% —
3734 VK055_1480 hypothetical protein ColabFold – – 0.352 No Hit 0.0% —
3735 VK055_1037 2Fe-2S iron-sulfur cluster binding domain protein AlphaFold + ColabFold –
GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0010124The chemical reactions and pathways resulting in the breakdown of phenylacetate. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. +36 total
0.352 Hit 26.7% 2.04e-09
3736 VK055_4097 hypothetical protein AlphaFold + ColabFold –
GO:0006364Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. GO:0006139Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
0.351 No Hit 0.0% —
3737 VK055_1059 hypothetical protein ColabFold – – 0.351 No Hit 0.0% —
3738 VK055_3512 divergent polysaccharide deacetylase family protein AlphaFold + ColabFold –
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
0.35 No Hit 0.0% —
3739 VK055_3093 hypothetical protein AlphaFold + ColabFold – – 0.35 No Hit 0.0% —
3740 VK055_1153 amidohydrolase family protein AlphaFold + ColabFold –
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0046872Binding to a metal ion. GO:0050118Catalysis of the reaction: H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + acetate. +14 total
0.35 No Hit 0.0% —
3741 VK055_0813 hypothetical protein ColabFold – – 0.35 No Hit 0.0% —
3742 VK055_4627 ROK family protein AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0006351The synthesis of an RNA transcript from a DNA template.
0.349 Hit 26.5% 3.44e-14
3743 VK055_4230 type VII secretion system (T7SS), usher family protein AlphaFold + ColabFold –
GO:0015473A porin that acts in the assembly of fimbria together with fimbrial chaperone. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0005515Binding to a protein. +25 total
0.349 No Hit 0.0% —
3744 VK055_3582 celllulose biosynthesis operon protein BcsF/YhjT bcsF AlphaFold + ColabFold – – 0.349 No Hit 0.0% —
3745 VK055_3202 ketol-acid reductoisomerase ilvC AlphaFold + ColabFold
1.1.1.86
GO:0004455Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0009082The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. +47 total
0.349 No Hit 0.0% —
3746 VK055_0233 narL transcriptional dual regulator narL AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. +25 total
0.349 No Hit 0.0% —
3747 VK055_0129 ribonuclease D rnd AlphaFold + ColabFold
3.1.13.5
GO:0033890Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides. GO:0003676Binding to a nucleic acid. GO:0006139Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. +69 total
0.349 Hit 25.5% 5.86e-10
3748 VK055_0085 hypothetical protein regulated by LexA yebG AlphaFold + ColabFold – – 0.349 No Hit 0.0% —
3749 VK055_3776 30S ribosomal protein S13 rpsM AlphaFold + ColabFold –
GO:0003735The action of a molecule that contributes to the structural integrity of the ribosome. GO:0003676Binding to a nucleic acid. GO:0003723Binding to an RNA molecule or a portion thereof. +69 total
0.348 Hit 27.3% 4.49e-06
3750 VK055_3690 hypothetical protein AlphaFold + ColabFold – – 0.348 No Hit 0.0% —
Page of 204 · 5081 total proteins