Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3126 KP13_05621 hypothetical protein AlphaFold + ColabFold – – 0.517 No Hit 0.0% —
3127 KP13_05237 hypothetical protein AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.517 No Hit 0.0% —
3128 KP13_04964 reverse transcriptase domain-containing protein AlphaFold + ColabFold –
GO:0003964Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.
0.517 No Hit 0.0% —
3129 KP13_04242 Arginine transport ATP-binding protein artP artP AlphaFold + ColabFold
7.4.2.1
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0003333The process in which an amino acid is transported across a membrane. +36 total
0.517 Hit 53.8% 1.71e-06
3130 KP13_04031 Phage major tail shaft subunit AlphaFold + ColabFold – – 0.517 No Hit 0.0% —
3131 KP13_01667 reverse transcriptase domain-containing protein AlphaFold + ColabFold – – 0.517 No Hit 0.0% —
3132 KP13_01340 putative transposase AlphaFold + ColabFold –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.517 No Hit 0.0% —
3133 KP13_00091 Phosphonoacetaldehyde hydrolase phnX AlphaFold + ColabFold
3.11.1.1
GO:0050194Catalysis of the reaction: H2O + phosphonoacetaldehyde = acetaldehyde + H+ + phosphate. GO:0019700The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.517 No Hit 0.0% —
3134 KP13_00011 ATPase ravA ravA AlphaFold + ColabFold –
GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
0.517 No Hit 0.0% —
3135 KP13_31925 Glutamine-binding periplasmic protein glnH AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015276Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
0.516 Hit 35.6% 4.48e-07
3136 KP13_06675 hypothetical protein AlphaFold + ColabFold – – 0.516 No Hit 0.0% —
3137 KP13_04853 DNA-binding protein AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.516 No Hit 0.0% —
3138 KP13_04655 hypothetical protein AlphaFold + ColabFold – – 0.516 No Hit 0.0% —
3139 KP13_03771 Imidazole glycerol phosphate synthase subunit hisH hisH AlphaFold + ColabFold
4.3.2.10 3.5.1.2
GO:0000105The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0016763Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +36 total
0.516 No Hit 0.0% —
3140 KP13_02938 Hydroxyacylglutathione hydrolase gloB AlphaFold + ColabFold
3.1.2.6
GO:0019243OBSOLETE. The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into pyruvate via the intermediate (R)-S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step. GO:0004416Catalysis of the reaction: an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H+. GO:0046872Binding to a metal ion.
0.516 Hit 36.1% 6.45e-21
3141 KP13_02786 hypothetical protein AlphaFold + ColabFold – – 0.516 No Hit 0.0% —
3142 KP13_01542 hypothetical protein AlphaFold + ColabFold – – 0.516 No Hit 0.0% —
3143 KP13_01162 Voltage-gated ClC-type chloride channel clcB clcB AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0005247Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0006821The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. +47 total
0.516 No Hit 0.0% —
3144 KP13_32246 Streptothricin acetyltransferase sat ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.515 No Hit 0.0% —
3145 KP13_31532 hypothetical protein AlphaFold + ColabFold – – 0.515 No Hit 0.0% —
3146 KP13_06722 hypothetical protein AlphaFold + ColabFold – – 0.515 No Hit 0.0% —
3147 KP13_05613 hypothetical protein AlphaFold + ColabFold – – 0.515 No Hit 0.0% —
3148 KP13_05482 Hydantoin racemase hyuE Experimental + ColabFold –
GO:0036361OBSOLETE. Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative. GO:0006807OBSOLETE. The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
0.515 No Hit 0.0% —
3149 KP13_04010 hypothetical protein ColabFold – – 0.515 No Hit 0.0% —
3150 KP13_03688 hypothetical protein AlphaFold + ColabFold – – 0.515 No Hit 0.0% —
Page of 234 · 5842 total proteins