Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
426 KP13_00679 Fe/S biogenesis protein nfuA nfuA AlphaFold + ColabFold –
GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0051604Any process leading to the attainment of the full functional capacity of a protein. GO:0016226The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. +25 total
0.387 No Hit 0.0% —
427 KP13_00680 Protein gntX gntX AlphaFold + ColabFold – – 0.673 No Hit 0.0% —
428 KP13_00682 hypothetical protein AlphaFold + ColabFold – – 0.348 No Hit 0.0% —
429 KP13_00683 Ferrous iron transport protein C feoC Experimental + AlphaFold + ColabFold – – 0.659 No Hit 0.0% —
430 KP13_00684 Ferrous iron transport protein B feoB Experimental + AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015093Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. GO:0006826The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. +14 total
0.993 No Hit 0.0% —
431 KP13_00688 Transcriptional regulatory protein ompR ompR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +58 total
0.363 No Hit 0.0% —
432 KP13_00689 Osmolarity sensor protein envZ envZ AlphaFold + ColabFold –
GO:0016310The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. GO:0016772Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +25 total
0.902 No Hit 0.0% —
433 KP13_00690 Phosphoenolpyruvate carboxykinase pckA AlphaFold + ColabFold
4.1.1.49
GO:0017076Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0006094The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. +47 total
0.267 No Hit 0.0% —
434 KP13_00691 hypothetical protein AlphaFold + ColabFold – – 0.271 No Hit 0.0% —
435 KP13_00692 33 kDa chaperonin hslO AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0051082Binding to an unfolded protein. GO:0006457The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. +25 total
0.294 No Hit 0.0% —
436 KP13_00693 Heat shock protein 15 hslR AlphaFold + ColabFold –
GO:0034605Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0043023Binding to a large ribosomal subunit. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +25 total
0.32 No Hit 0.0% —
437 KP13_00694 Haloacid dehydrogenase/epoxide hydrolase AlphaFold + ColabFold – – 0.755 No Hit 0.0% —
438 KP13_00697 Penicillin-binding protein 1A mrcA AlphaFold + ColabFold
2.4.99.28 3.4.16.4
GO:0008658Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +710 total
0.568 No Hit 0.0% —
439 KP13_00698 hypothetical protein AlphaFold + ColabFold – – 0.669 No Hit 0.0% —
440 KP13_00699 hypothetical protein AlphaFold + ColabFold – – 0.715 No Hit 0.0% —
441 KP13_00700 hypothetical protein ColabFold – – 0.23 No Hit 0.0% —
442 KP13_00701 hypothetical protein AlphaFold + ColabFold – – 0.45 No Hit 0.0% —
443 KP13_00702 Protein transport protein hofQ hofQ AlphaFold + ColabFold –
GO:0009306The controlled release of proteins from a cell. GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
0.811 No Hit 0.0% —
444 KP13_00705 Protein damX damX AlphaFold + ColabFold –
GO:0042834Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls. GO:0030428A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:0032506A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
0.103 No Hit 0.0% —
445 KP13_00706 DNA adenine methylase dam AlphaFold + ColabFold
2.1.1.72
GO:0009007Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0003676Binding to a nucleic acid. +710 total
0.386 No Hit 0.0% —
446 KP13_00708 Phosphoglycolate phosphatase gph AlphaFold + ColabFold
3.1.3.18
GO:0008967Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.896 No Hit 0.0% —
447 KP13_00710 Siroheme synthase 2 cysG2 AlphaFold + ColabFold –
GO:0004851Catalysis of the reaction: uroporphyrinogen III + 2 S-adenosyl-L-methionine = precorrin-2 + 2 S-adenosyl-L-homocysteine + H+. GO:0051266Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. +58 total
0.579 No Hit 0.0% —
448 KP13_00711 Nitrite reductase [NAD(P)H] small subunit nirD AlphaFold + ColabFold
1.7.1.15
GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0008942Catalysis of the reaction: NH4+ + 3 NAD(P)+ + 2 H2O = nitrite + 3 NAD(P)H + 5 H+. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +36 total
0.105 No Hit 0.0% —
449 KP13_00713 hypothetical protein AlphaFold + ColabFold – – 0.717 No Hit 0.0% —
450 KP13_00714 Cytosine deaminase codA AlphaFold + ColabFold –
GO:0016810Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. GO:0004131Catalysis of the reaction: cytosine + H2O = uracil + NH4+. GO:0035888Catalysis of the reaction: H+ + H2O + isoguanine = NH4+ + xanthine. +25 total
0.287 No Hit 0.0% —
Page of 234 · 5842 total proteins