Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4526 KP13_04804 Type IV secretion system protein virB10 virB10 AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.514 No Hit 0.0% —
4527 KP13_04805 Type IV secretion system protein virB9 virB9 AlphaFold + ColabFold – – No map 0.432 No Hit 0.0% —
4528 KP13_04806 Type IV secretion system protein ptlE ptlE AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.311 No Hit 0.0% —
4529 KP13_04807 hypothetical protein AlphaFold + ColabFold – – No map No pocket No Hit 0.0% —
4530 KP13_04808 Type IV secretion system protein virB6 virB6 AlphaFold + ColabFold –
GO:0030255The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.878 No Hit 0.0% —
4531 KP13_04809 hypothetical protein AlphaFold + ColabFold – – No map 0.222 No Hit 0.0% —
4532 KP13_04810 type IV secretion system VirB5 component AlphaFold + ColabFold – – No map 0.4 No Hit 0.0% —
4533 KP13_04811 Type IV secretion system protein virB4 virB4 AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.728 No Hit 0.0% —
4534 KP13_04812 Type IV secretion system protein ptlA ptlA AlphaFold + ColabFold – – No map 0.962 No Hit 0.0% —
4535 KP13_04813 Type IV secretion system protein virB1 virB1 AlphaFold + ColabFold – – No map 0.489 No Hit 0.0% —
4536 KP13_04814 hypothetical protein ColabFold – – No map 0.018 No Hit 0.0% —
4537 KP13_04815 hypothetical protein ColabFold – – No map 0.663 No Hit 0.0% —
4538 KP13_04816 hypothetical protein AlphaFold + ColabFold –
GO:0008270Binding to a zinc ion (Zn). GO:1900378Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.
No map 0.266 No Hit 0.0% —
4539 KP13_04817 hypothetical protein AlphaFold + ColabFold – – No map 0.697 No Hit 0.0% —
4540 KP13_04818 hypothetical protein AlphaFold + ColabFold – – No map 0.297 No Hit 0.0% —
4541 KP13_04819 hypothetical protein AlphaFold + ColabFold – – No map 0.15 No Hit 0.0% —
4542 KP13_04820 hypothetical protein AlphaFold + ColabFold – – No map 0.458 No Hit 0.0% —
4543 KP13_04821 Pesticin receptor fyuA AlphaFold + ColabFold –
GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0015891The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015343Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in). +14 total
No map 0.828 No Hit 0.0% —
4544 KP13_04824 thiazolinyl-S-HMWP1 reductase AlphaFold + ColabFold –
GO:0000166Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
No map 0.542 No Hit 0.0% —
4545 KP13_04827 AraC-type transcriptional regulator for yersiniabactin uptake AlphaFold + ColabFold –
GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
No map 0.92 No Hit 0.0% —
4546 KP13_04831 Isochorismate synthase/isochorismate-pyruvate lyase mbtI mbtI AlphaFold + ColabFold –
GO:0009058A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. GO:0016833Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid. GO:0008909Catalysis of the reaction: chorismate = isochorismate. +25 total
No map 0.405 No Hit 0.0% —
4547 KP13_04832 hypothetical protein AlphaFold + ColabFold –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.02 No Hit 0.0% —
4548 KP13_04833 Protein mtfA mtfA Experimental + ColabFold –
GO:0008237Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
No map 0.361 No Hit 0.0% —
4549 KP13_04834 Outer membrane protein S1 ompS1 AlphaFold + ColabFold –
GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0034220A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. +25 total
No map 0.99 No Hit 0.0% —
4550 KP13_04835 Outer membrane protein N precursor AlphaFold + ColabFold –
GO:0051301The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.963 No Hit 0.0% —
Page of 234 · 5842 total proteins