Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5701 KP13_32082 hypothetical protein ColabFold – – 0.356 No Hit 0.0% —
5702 KP13_32083 putative exonuclease AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0008408Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. GO:0006259Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
0.331 No Hit 0.0% —
5703 KP13_32084 transposase for transposon gamma-delta-like protein ColabFold –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
0.76 No Hit 0.0% —
5704 KP13_32085 hypothetical protein AlphaFold + ColabFold – – 0.094 No Hit 0.0% —
5705 KP13_32086 conjugal transfer traI-like protein AlphaFold + ColabFold – – 0.563 No Hit 0.0% —
5706 KP13_32087 conjugal transfer TraD-like protein AlphaFold + ColabFold – – 0.623 No Hit 0.0% —
5707 KP13_32089 modification methylase HhaI hhaIM AlphaFold + ColabFold
2.1.1.37
GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0003886Catalysis of the reaction: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H+ + S-adenosyl-L-homocysteine. GO:0009307A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme. +14 total
0.298 No Hit 0.0% —
5708 KP13_32090 hypothetical protein ColabFold – – 0.568 No Hit 0.0% —
5709 KP13_32092 hypothetical protein AlphaFold + ColabFold – – 0.529 No Hit 0.0% —
5710 KP13_32093 Insertion sequence IS408 putative ATP-binding protein AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
0.877 No Hit 0.0% —
5711 KP13_32094 hypothetical protein AlphaFold + ColabFold – – 0.906 No Hit 0.0% —
5712 KP13_32095 peptidase family S49 AlphaFold + ColabFold –
GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. GO:0008233Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. GO:0008236Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
0.451 No Hit 0.0% —
5713 KP13_32096 hypothetical protein AlphaFold + ColabFold – – 0.185 No Hit 0.0% —
5714 KP13_32097 hypothetical protein AlphaFold + ColabFold – – 0.54 No Hit 0.0% —
5715 KP13_32098 Lambda repressor-like, DNA-binding domain-containing protein AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.368 No Hit 0.0% —
5716 KP13_32099 F-type conjugal transfer TraF-like protein AlphaFold + ColabFold – – 0.284 No Hit 0.0% —
5717 KP13_32100 F-type conjugal transfer TraG-like protein AlphaFold + ColabFold – – 0.703 No Hit 0.0% —
5718 KP13_32101 conjugal transfer TraH-like (IncFII R100) protein AlphaFold + ColabFold – – 0.356 No Hit 0.0% —
5719 KP13_32102 hypothetical protein AlphaFold + ColabFold – – 0.5 No Hit 0.0% —
5720 KP13_32103 initiator RepB protein repB AlphaFold + ColabFold –
GO:0003887Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. GO:0006270The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding.
0.146 No Hit 0.0% —
5721 KP13_32104 hypothetical protein AlphaFold + ColabFold – – No pocket No Hit 0.0% —
5722 KP13_32105 type IV conjugative transfer system VirB1-like protein AlphaFold + ColabFold – – 0.248 No Hit 0.0% —
5723 KP13_32107 hypothetical protein AlphaFold + ColabFold – – 0.247 No Hit 0.0% —
5724 KP13_32108 hypothetical protein ColabFold – – 0.809 No Hit 0.0% —
5725 KP13_32111 putative replication initiation protein ColabFold – – 0.352 No Hit 0.0% —
Page of 234 · 5842 total proteins