Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5192 proteins Structure: AlphaFold

Scoring formula None

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Structure: AlphaFold ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
151 KP13_02807 SH3-like domain-containing protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
0.984 No Hit 0.0% —
152 KP13_02582 6-phospho-beta-glucosidase ascB ascB AlphaFold + ColabFold –
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.984 Hit 39.6% 1.80e-14
153 KP13_01676 hypothetical protein AlphaFold + ColabFold – – 0.984 No Hit 0.0% —
154 KP13_01124 putative phospholipid-binding protein mlaC mlaC AlphaFold + ColabFold – – 0.984 No Hit 0.0% —
155 KP13_00703 Shikimate kinase 1 aroK AlphaFold + ColabFold
2.7.1.71
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0000287Binding to a magnesium (Mg) ion. +47 total
0.984 Hit 29.5% 1.81e-07
156 KP13_04712 Respiratory nitrate reductase 1 alpha chain narG AlphaFold + ColabFold
1.7.5.1
GO:0009325An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor. GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. +811 total
0.983 No Hit 0.0% —
157 KP13_04449 Tellurite resistance protein tehA tehA AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +47 total
0.983 No Hit 0.0% —
158 KP13_03821 Putative permease perM perM AlphaFold + ColabFold – – 0.983 No Hit 0.0% —
159 KP13_03559 hypothetical protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.983 Hit 27.5% 9.99e-30
160 KP13_03514 hypothetical protein AlphaFold + ColabFold – – 0.983 No Hit 0.0% —
161 KP13_02563 6-phospho-beta-glucosidase gmuD AlphaFold + ColabFold –
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.983 Hit 32.8% 4.51e-28
162 KP13_00987 NADH-quinone oxidoreductase subunit H nuoH AlphaFold + ColabFold
7.1.1.-
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0003954Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor. +36 total
0.983 Hit 41.5% 2.51e-61
163 KP13_00476 hypothetical protein AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.983 No Hit 0.0% —
164 KP13_32072 resolvase resD AlphaFold + ColabFold –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.982 No Hit 0.0% —
165 KP13_31571 Inner membrane transporter AlphaFold + ColabFold –
GO:0015833The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:1904680Enables the transfer of a peptide from one side of a membrane to the other. +58 total
0.982 Hit 31.7% 2.17e-17
166 KP13_04946 Glucans biosynthesis glucosyltransferase H mdoH AlphaFold + ColabFold
2.4.1.-
GO:0016758Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0009250The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.
0.982 No Hit 0.0% —
167 KP13_04069 Zinc-type alcohol dehydrogenase-like protein AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0008270Binding to a zinc ion (Zn).
0.982 Hit 31.7% 1.75e-07
168 KP13_03488 putative oxidoreductase protein AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
0.982 No Hit 0.0% —
169 KP13_00598 putative alcohol dehydrogenase AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0046872Binding to a metal ion. GO:0004022Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
0.982 Hit 26.4% 1.78e-28
170 KP13_00366 putative branched-chain amino acid transport protein AlphaFold + ColabFold – – 0.982 No Hit 0.0% —
171 KP13_26403 Phosphatidylglycerophosphatase B pgpB AlphaFold + ColabFold
3.6.1.27
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0050380Catalysis of the reaction: di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate.
0.981 No Hit 0.0% —
172 KP13_04562 putative oxidoreductase AlphaFold + ColabFold
1.2.1.-
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
0.981 Hit 36.4% 2.97e-12
173 KP13_03859 Dihydroorotate dehydrogenase pyrD AlphaFold + ColabFold
1.3.5.2
GO:0006207The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +69 total
0.981 Hit 47.1% 1.05e-27
174 KP13_03263 tetratricopeptide-like helical domain-containing protein AlphaFold + ColabFold –
GO:0070206The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits. GO:0005515Binding to a protein. GO:0051301The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. +25 total
0.981 No Hit 0.0% —
175 KP13_01878 Dihydrolipoyl dehydrogenase lpdA AlphaFold + ColabFold
1.8.1.4
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0050660Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. GO:0016668Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP. +47 total
0.981 Hit 52.8% 7.04e-16
Page of 208 · 5192 total proteins