Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
2451 KP13_01758 HlyD family secretion protein AlphaFold + ColabFold – – No map 0.5 No Hit 0.0% —
2452 KP13_01760 hypothetical protein AlphaFold + ColabFold – – No map 0.487 No Hit 0.0% —
2453 KP13_01762 DNA helicase domain-containing protein AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0003678Unwinding of a DNA helix, driven by ATP hydrolysis. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +36 total
No map 0.246 No Hit 0.0% —
2454 KP13_01763 Glutathione transferase fosA fosA Experimental + ColabFold – – No map 0.53 No Hit 0.0% —
2455 KP13_01764 LysR family transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.921 No Hit 0.0% —
2456 KP13_01766 Ribose transport system permease protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +14 total
No map 0.882 No Hit 0.0% —
2457 KP13_01767 Ribose transport system permease protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +14 total
No map 0.918 No Hit 0.0% —
2458 KP13_01769 putative ribose ABC transporter substrate-binding protein Experimental + ColabFold – – No map 0.484 No Hit 0.0% —
2459 KP13_01771 HlyD family secretion protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
No map 0.607 No Hit 0.0% —
2460 KP13_01773 Inner membrane transport permease AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0140359Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
No map 0.763 No Hit 0.0% —
2461 KP13_01774 hypothetical protein AlphaFold + ColabFold – – No map 0.649 No Hit 0.0% —
2462 KP13_01775 hypothetical protein AlphaFold + ColabFold – – No map 0.317 No Hit 0.0% —
2463 KP13_01777 hypothetical protein ColabFold – – No map 0.185 No Hit 0.0% —
2464 KP13_01778 D,D-heptose 1,7-bisphosphate phosphatase gmhB AlphaFold + ColabFold
3.1.3.-
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0016791Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +36 total
No map 0.448 No Hit 0.0% —
2465 KP13_01780 D-methionine transport system permease protein metI metI AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
No map 0.655 No Hit 0.0% —
2466 KP13_01781 D-methionine-binding lipoprotein metQ metQ AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0015821The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
No map 0.597 No Hit 0.0% —
2467 KP13_01782 Protein rcsF rcsF AlphaFold + ColabFold –
GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0035556The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. GO:0031241The leaflet of a outer cell membrane that faces the periplasm, including any protein embedded in, attached to, or peripherally associated with it.
No map 0.445 No Hit 0.0% —
2468 KP13_01785 hypothetical protein AlphaFold + ColabFold – – No map 0.319 No Hit 0.0% —
2469 KP13_01786 Lipoprotein NlpE nlpE AlphaFold + ColabFold – – No map 0.436 No Hit 0.0% —
2470 KP13_01787 peptidyl-tRNA hydrolase domain-containing protein AlphaFold + ColabFold
3.1.1.29
GO:0003747Involved in catalyzing the release of a nascent polypeptide chain from a ribosome. GO:0006415The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +47 total
No map 0.212 No Hit 0.0% —
2471 KP13_01788 hypothetical protein AlphaFold + ColabFold – – No map 0.507 No Hit 0.0% —
2472 KP13_01789 hypothetical protein AlphaFold + ColabFold – – No map 0.483 No Hit 0.0% —
2473 KP13_01790 Protein rof rof AlphaFold + ColabFold – – No map 0.048 No Hit 0.0% —
2474 KP13_01791 tRNA(Ile)-lysidine synthase tilS AlphaFold + ColabFold
6.3.4.19
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0016879Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0008033The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. +47 total
No map 0.65 No Hit 0.0% —
2475 KP13_01792 Glyoxalase domain-containing protein AlphaFold + ColabFold –
GO:0046872Binding to a metal ion.
No map 0.238 No Hit 0.0% —
Page of 234 · 5842 total proteins