Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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5572 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5526 PA3122 transcriptional regulator PA3122 AlphaFold –
GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0000976Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
No pocket No Hit N/A —
5527 PA3367 hypothetical protein PA3367 AlphaFold – – No pocket No Hit N/A —
5528 PA3833 hypothetical protein PA3833 AlphaFold – – No pocket No Hit N/A —
5529 PA1006 hypothetical protein PA1006 AlphaFold –
GO:0042128The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances. GO:0044010A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
No pocket No Hit N/A —
5530 PA4426 hypothetical protein PA4426 AlphaFold – – No pocket No Hit N/A —
5531 PA4563 30S ribosomal protein S20 rpsT, PA4563 AlphaFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0015935The smaller of the two subunits of a ribosome. GO:0070181Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA. +47 total
No pocket No Hit N/A —
5532 PA0431 hypothetical protein PA0431 Experimental + AlphaFold –
GO:0008893Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H+. GO:0046872Binding to a metal ion.
No pocket Hit 32.6% 1.73e-07
5533 PA2504 hypothetical protein PA2504 AlphaFold – – No pocket No Hit N/A —
5534 PA5526 hypothetical protein PA5526 AlphaFold – – No pocket No Hit N/A —
5535 PA2462 hypothetical protein PA2462 UnavailableNo structure available — sequence may exceed the prediction length limit –
GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks.
No structure No structure No structure No structure
5536 PA3203 hypothetical protein PA3203 AlphaFold – – No pocket No Hit N/A —
5537 PA3664 hypothetical protein PA3664 Experimental + AlphaFold – – No pocket No Hit N/A —
5538 PA3284 hypothetical protein PA3284 AlphaFold – – No pocket No Hit N/A —
5539 PA0993 chaperone CupC2 cupC2, PA0993 AlphaFold –
GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. GO:0044183Binding to a protein or a protein-containing complex to assist the protein folding process. GO:0071555A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. +25 total
No pocket No Hit N/A —
5540 PA1774 hypothetical protein crfX, PA1774 AlphaFold – – No pocket No Hit N/A —
5541 PA2501 hypothetical protein PA2501 AlphaFold – – No pocket No Hit N/A —
5542 PA2190 hypothetical protein PA2190 AlphaFold – – No pocket No Hit N/A —
5543 PA3350 flagellar basal body P-ring biosynthesis protein FlgA PA3350 AlphaFold –
GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). GO:0044780The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility. GO:0071973Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
No pocket No Hit N/A —
5544 PA0736a hypothetical protein ColabFold – – No pocket No Hit N/A —
5545 PA3143 hypothetical protein PA3143 AlphaFold – – No pocket No Hit N/A —
5546 PA1404 hypothetical protein PA1404 AlphaFold – – No pocket No Hit N/A —
5547 PA3031 hypothetical protein PA3031 AlphaFold – – No pocket No Hit N/A —
5548 PA0578 hypothetical protein PA0578 AlphaFold –
GO:0016884Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen.
No pocket No Hit N/A —
5549 PA0637 hypothetical protein PA0637, MF2 AlphaFold – – No pocket No Hit N/A —
5550 PA4577 hypothetical protein PA4577 AlphaFold –
GO:0008270Binding to a zinc ion (Zn).
No pocket No Hit N/A —
Page of 223 · 5572 total proteins