Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5192 / 5842 proteins Structure: AlphaFold

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Structure: AlphaFold ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4126 KP13_04520 2-halobenzoate 1,2-dioxygenase large subunit cbdA AlphaFold + ColabFold –
GO:0044237OBSOLETE. The chemical reactions and pathways by which individual cells transform chemical substances. GO:0005506Binding to an iron (Fe) ion. GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. +14 total
0.294 No Hit 0.0% —
4127 KP13_04318 hypothetical protein AlphaFold + ColabFold –
GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
0.294 No Hit 0.0% —
4128 KP13_03681 putative lipoprotein AlphaFold + ColabFold – – 0.294 No Hit 0.0% —
4129 KP13_03330 putative Filamentous hemagglutinin AlphaFold + ColabFold – – 0.294 No Hit 0.0% —
4130 KP13_02725 hypothetical protein AlphaFold + ColabFold – – 0.294 No Hit 0.0% —
4131 KP13_02145 hypothetical protein AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.294 No Hit 0.0% —
4132 KP13_02122 Amino acid ABC superfamily ATP binding cassette transporter, binding protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015276Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0005576The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. +25 total
0.294 Hit 42.5% 3.55e-06
4133 KP13_00692 33 kDa chaperonin hslO AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0051082Binding to an unfolded protein. GO:0006457The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. +25 total
0.294 No Hit 0.0% —
4134 KP13_00272 Dipeptide transport ATP-binding protein dppF dppF AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0015833The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. +25 total
0.294 Hit 39.1% 6.48e-08
4135 KP13_32238 Ethanolamine ammonia-lyase heavy chain eutB AlphaFold + ColabFold
4.3.1.7
GO:0006520The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. GO:0008851Catalysis of the reaction: ethanolamine = acetaldehyde + NH4+. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +47 total
0.293 No Hit 0.0% —
4136 KP13_04253 Putrescine transport ATP-binding protein potG potG AlphaFold + ColabFold
7.6.2.11
GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0015417Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in). +58 total
0.293 Hit 34.7% 4.90e-24
4137 KP13_04064 Glyoxalase/bleomycin resistance protein/dioxygenase AlphaFold + ColabFold –
GO:0051213Catalysis of the incorporation of both atoms of molecular oxygen (O2) into the substrate.
0.293 No Hit 0.0% —
4138 KP13_02348 Glycine cleavage system transcriptional activator gcvA AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. +14 total
0.293 No Hit 0.0% —
4139 KP13_01816 Carbohydrate diacid regulator cdaR AlphaFold + ColabFold – – 0.293 No Hit 0.0% —
4140 KP13_01035 hypothetical protein AlphaFold + ColabFold – – 0.293 No Hit 0.0% —
4141 KP13_00587 Superoxide dismutase Mn sodA AlphaFold + ColabFold
1.15.1.1
GO:0004784Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + H2O2. GO:0006801The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. GO:0046872Binding to a metal ion. +25 total
0.293 Hit 54.3% 2.20e-11
4142 KP13_31998 Glutathione S-transferase GstB gstB AlphaFold + ColabFold
2.5.1.18
GO:0004364Catalysis of the reaction: RX + glutathione = an S-substituted glutathione + a halide anion + H+.
0.292 Hit 26.2% 5.20e-09
4143 KP13_05582 thermonuclease family protein AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
0.292 No Hit 0.0% —
4144 KP13_04838 Very short patch repair protein vsr AlphaFold + ColabFold
3.1.-.-
GO:0006298A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
0.292 No Hit 0.0% —
4145 KP13_02860 Autoinducer 2 import ATP-binding protein LsrA lsrA AlphaFold + ColabFold
7.6.2.13
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.292 Hit 35.7% 3.51e-10
4146 KP13_02730 Ribosomal RNA small subunit methyltransferase E rsmE AlphaFold + ColabFold
2.1.1.193
GO:0006364Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +25 total
0.292 No Hit 0.0% —
4147 KP13_00550 Inner membrane protein AlphaFold + ColabFold – – 0.292 No Hit 0.0% —
4148 KP13_04682 hypothetical protein AlphaFold + ColabFold –
GO:0004521Catalysis of the cleavage of ester linkages within ribonucleic acid by creating internal breaks.
0.291 No Hit 0.0% —
4149 KP13_04388 hypothetical protein AlphaFold + ColabFold – – 0.291 No Hit 0.0% —
4150 KP13_03767 ATP phosphoribosyltransferase hisG AlphaFold + ColabFold
2.4.2.17
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0000105The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0003879Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate. +25 total
0.29 No Hit 0.0% —
Page of 208 · 5192 total proteins