Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4426 KP13_31606 Protein phnB phnB AlphaFold + ColabFold – – 0.32 No Hit 0.0% —
4427 KP13_05747 hypothetical protein ColabFold – – 0.32 No Hit 0.0% —
4428 KP13_03129 Quaternary ammonium compound-resistance protein qacE AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. +14 total
0.32 No Hit 0.0% —
4429 KP13_02967 Rod shape-determining protein mreC mreC AlphaFold + ColabFold –
GO:0008360Any process that modulates the surface configuration of a cell. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.32 No Hit 0.0% —
4430 KP13_01941 hypothetical protein ColabFold – – 0.32 No Hit 0.0% —
4431 KP13_00693 Heat shock protein 15 hslR AlphaFold + ColabFold –
GO:0034605Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0043023Binding to a large ribosomal subunit. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +25 total
0.32 No Hit 0.0% —
4432 KP13_00433 Acetyl-coenzyme A synthetase acs AlphaFold + ColabFold
6.2.1.1
GO:0019427OBSOLETE. The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate. GO:0016208Binding to AMP, adenosine monophosphate. GO:0003987Catalysis of the reaction: acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate. +47 total
0.32 Hit 52.2% 1.61e-25
4433 KP13_06880 hypothetical protein AlphaFold + ColabFold – – 0.319 No Hit 0.0% —
4434 KP13_01866 Blue copper oxidase cueO cueO AlphaFold + ColabFold
1.16.3.4
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0005507Binding to a copper (Cu) ion.
0.319 No Hit 0.0% —
4435 KP13_01785 hypothetical protein AlphaFold + ColabFold – – 0.319 No Hit 0.0% —
4436 KP13_01038 Chorismate synthase aroC AlphaFold + ColabFold
4.2.3.5
GO:0004107Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. GO:0009073The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.319 No Hit 0.0% —
4437 KP13_00628 putative GTP-binding protein engB engB Experimental + ColabFold –
GO:0005525Binding to GTP, guanosine triphosphate.
0.319 Hit 35.1% 5.93e-19
4438 KP13_31748 Ferrous iron transport protein A feoA Experimental + ColabFold –
GO:0046914Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
0.318 No Hit 0.0% —
4439 KP13_17708 putative transpeptidase AlphaFold + ColabFold –
GO:0016740Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. GO:0004180Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain. GO:0071555A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. +25 total
0.318 No Hit 0.0% —
4440 KP13_05635 hypothetical protein AlphaFold + ColabFold – – 0.318 No Hit 0.0% —
4441 KP13_05396 N-succinylarginine dihydrolase AlphaFold + ColabFold
3.5.3.23
GO:0009015Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H2O + 2 H+ = N(2)-succinyl-L-ornithine + CO2 + 2 NH4. GO:0006525The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. GO:0019544OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-arginine into other compounds, including L-glutamate. +14 total
0.318 No Hit 0.0% —
4442 KP13_04855 hypothetical protein AlphaFold + ColabFold – – 0.318 No Hit 0.0% —
4443 KP13_04707 putative HTH-type transcriptional regulator AlphaFold + ColabFold –
GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0043200Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
0.318 No Hit 0.0% —
4444 KP13_04532 hypothetical protein AlphaFold + ColabFold
2.7.4.-
GO:0008976Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1). GO:0006793The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus.
0.318 No Hit 0.0% —
4445 KP13_04160 hypothetical protein ColabFold – – 0.318 No Hit 0.0% —
4446 KP13_03770 Histidine biosynthesis bifunctional protein hisB AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0000105The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0004424Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O. +36 total
0.318 No Hit 0.0% —
4447 KP13_03714 Cation efflux system protein cusB cusB AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0046872Binding to a metal ion. +58 total
0.318 No Hit 0.0% —
4448 KP13_02963 hypothetical protein AlphaFold + ColabFold – – 0.318 No Hit 0.0% —
4449 KP13_02803 Glycogen synthesis protein glgS glgS AlphaFold + ColabFold –
GO:1902201Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility. GO:1900191Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.
0.318 No Hit 0.0% —
4450 KP13_01947 Ribosomal large subunit pseudouridine synthase A rluA AlphaFold + ColabFold
5.4.99.-
GO:0003723Binding to an RNA molecule or a portion thereof. GO:0001522The intramolecular conversion of uridine to pseudouridine within an RNA molecule. GO:0009451The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. +58 total
0.318 Hit 48.1% 1.98e-11
Page of 234 · 5842 total proteins