Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4851 KP13_31979 hypothetical protein AlphaFold + ColabFold – – 0.254 No Hit 0.0% —
4852 KP13_31817 hypothetical protein ColabFold – – 0.254 No Hit 0.0% —
4853 KP13_05051 insertion element IS1 protein InsB ColabFold –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.254 No Hit 0.0% —
4854 KP13_03932 isochorismatase-like hydrolase AlphaFold + ColabFold –
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
0.254 Hit 27.4% 5.70e-06
4855 KP13_03411 putative enterobactin synthetase, component D AlphaFold + ColabFold –
GO:0016780Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor). GO:0008897Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. GO:0000287Binding to a magnesium (Mg) ion. +36 total
0.254 No Hit 0.0% —
4856 KP13_00613 PilT domain-containing protein AlphaFold + ColabFold –
GO:0004540Catalysis of the cleavage of phosphodiester bonds in chains of RNA.
0.254 No Hit 0.0% —
4857 KP13_02727 Galactose-proton symporter galP AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +36 total
0.253 Hit 37.6% 1.09e-12
4858 KP13_02191 tRNA-modifying protein AlphaFold + ColabFold –
GO:0009451The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. GO:0005542Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +25 total
0.253 No Hit 0.0% —
4859 KP13_01313 hypothetical protein ColabFold – – 0.253 No Hit 0.0% —
4860 KP13_03978 hypothetical protein ColabFold – – 0.252 No Hit 0.0% —
4861 KP13_02830 Positive transcription regulator evgA evgA AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.252 No Hit 0.0% —
4862 KP13_02581 hypothetical protein AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0016788Catalysis of the hydrolysis of any ester bond. GO:0016070The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. +14 total
0.252 No Hit 0.0% —
4863 KP13_02436 hypothetical protein AlphaFold + ColabFold –
GO:0016740Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
0.252 No Hit 0.0% —
4864 KP13_05591 hypothetical protein AlphaFold + ColabFold – – 0.251 No Hit 0.0% —
4865 KP13_05223 putative lipoprotein AlphaFold + ColabFold – – 0.251 No Hit 0.0% —
4866 KP13_04394 Ribosomal small subunit pseudouridine synthase A rsuA AlphaFold + ColabFold
5.4.99.-
GO:0009451The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. GO:0009982Catalysis of the reaction: a uridine in RNA = a pseudouridine in RNA. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. GO:0001522The intramolecular conversion of uridine to pseudouridine within an RNA molecule. +58 total
0.251 No Hit 0.0% —
4867 KP13_04248 putative transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +47 total
0.251 No Hit 0.0% —
4868 KP13_02792 Esterase Experimental + ColabFold – – 0.251 No Hit 0.0% —
4869 KP13_01201 Inner membrane ABC transporter permease protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.251 No Hit 0.0% —
4870 KP13_00686 hypothetical protein AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0006139Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.251 Hit 37.9% 8.37e-07
4871 KP13_05496 HTH-type transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. +14 total
0.25 No Hit 0.0% —
4872 KP13_04098 FMN-dependent NADH-azoreductase 4 azoR4 Experimental + ColabFold –
GO:0016655Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. GO:0010181Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
0.25 No Hit 0.0% —
4873 KP13_01507 hypothetical protein AlphaFold + ColabFold – – 0.25 No Hit 0.0% —
4874 KP13_01172 hypothetical protein AlphaFold + ColabFold – – 0.25 No Hit 0.0% —
4875 KP13_00827 signal transduction response regulator protein AlphaFold + ColabFold –
GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0008134Binding to a transcription factor, a protein required to initiate or regulate transcription. +36 total
0.25 No Hit 0.0% —
Page of 234 · 5842 total proteins