Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
5842 / 5842 proteins
No filters or custom sorting applied — click to see defaults

Scoring formula None

Sorted by Druggability (P2Rank preferred) (descending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4976 KP13_05623 DNA-binding trans-acting positive regulator mgA mgA AlphaFold DB model + ColabFold model – – No map N/A 0.089 No Hit 0.0% —
4977 KP13_04032 Phage tail assembly chaperone AlphaFold DB model + ColabFold model – – No map 0.089 0.162 No Hit 0.0% —
4978 KP13_03655 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.089 No Hit 0.0% —
4979 KP13_03289 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
No map 0.089 0.794 No Hit 0.0% —
4980 KP13_02057 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.089 0.794 No Hit 0.0% —
4981 KP13_01264 Soluble cytochrome b562 cybC AlphaFold DB model + ColabFold model –
GO:0022900A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors. GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). GO:0005506Binding to an iron (Fe) ion. +25 total
No map 0.089 0.856 No Hit 0.0% —
4982 KP13_00411 Alpha-glucoside transport system permease protein aglF aglF AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.089 0.872 No Hit 0.0% —
4983 KP13_32044 putative transposase AlphaFold DB model + ColabFold model – – No map 0.088 0.546 No Hit 0.0% —
4984 KP13_31996 putative transposase AlphaFold DB model + ColabFold model – – No map 0.088 0.546 No Hit 0.0% —
4985 KP13_02963 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.088 0.318 No Hit 0.0% —
4986 KP13_02379 hypothetical protein ColabFold model – – No map 0.088 0.571 No Hit 0.0% —
4987 KP13_00587 Superoxide dismutase Mn sodA AlphaFold DB model + ColabFold model
1.15.1.1
GO:0004784Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + H2O2. GO:0006801The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. GO:0046872Binding to a metal ion. +25 total
No map 0.088 0.293 Hit 54.3% 2.20e-11
4988 KP13_06665 RepAC1 protein (modular protein) repAC1 AlphaFold DB model + ColabFold model – – No map 0.087 0.893 No Hit 0.0% —
4989 KP13_03510 putative ABC transporter permease protein AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
No map 0.087 0.746 No Hit 0.0% —
4990 KP13_03117 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.087 0.15 No Hit 0.0% —
4991 KP13_03005 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.087 No Hit 0.0% —
4992 KP13_01674 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.087 0.395 No Hit 0.0% —
4993 KP13_01455 hypothetical protein ColabFold model – – No map 0.087 0.906 No Hit 0.0% —
4994 KP13_01354 Transcription antitermination protein nusG nusG AlphaFold DB model + ColabFold model –
GO:0140673A chromatin remodeling process that reestablishes the chromatin structure following the passage of RNA polymerase II during transcription elongation, thus preventing cryptic transcription initiation. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0032784Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. +47 total
No map 0.087 0.408 No Hit 0.0% —
4995 KP13_05025 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.086 0.04 No Hit 0.0% —
4996 KP13_04732 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.086 0.924 No Hit 0.0% —
4997 KP13_03960 hypothetical protein ColabFold model – – No map N/A 0.086 No Hit 0.0% —
4998 KP13_03072 putative transmembrane protein ColabFold model – – No map 0.086 0.444 No Hit 0.0% —
4999 KP13_01201 Inner membrane ABC transporter permease protein AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.086 0.251 No Hit 0.0% —
5000 KP13_00868 Exodeoxyribonuclease 7 large subunit xseA AlphaFold DB model + ColabFold model
3.1.11.6
GO:0008855Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides. GO:0003676Binding to a nucleic acid. GO:0006308The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. +25 total
No map 0.086 0.29 No Hit 0.0% —
Page of 234 · 5842 total proteins