Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4951 KP13_05248 hypothetical protein AlphaFold + ColabFold – – 0.235 No Hit 0.0% —
4952 KP13_02886 Pirin-like protein AlphaFold + ColabFold – – 0.235 No Hit 0.0% —
4953 KP13_02672 hypothetical protein AlphaFold + ColabFold – – 0.235 No Hit 0.0% —
4954 KP13_06744 thermonuclease family protein AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0004518Catalysis of the cleavage of ester linkages within nucleic acids. GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks. +14 total
0.234 No Hit 0.0% —
4955 KP13_02828 hypothetical protein AlphaFold + ColabFold – – 0.234 No Hit 0.0% —
4956 KP13_02667 hypothetical protein ColabFold – – 0.234 No Hit 0.0% —
4957 KP13_01858 Aspartate 1-decarboxylase panD AlphaFold + ColabFold –
GO:0004068Catalysis of the reaction: L-aspartate = beta-alanine + CO2. GO:0006523The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.
0.234 No Hit 0.0% —
4958 KP13_01086 putative excinuclease ABC AlphaFold + ColabFold – – 0.234 No Hit 0.0% —
4959 KP13_32024 hypothetical protein ColabFold – – 0.233 No Hit 0.0% —
4960 KP13_32007 hypothetical protein AlphaFold + ColabFold – – 0.233 No Hit 0.0% —
4961 KP13_05553 membrane complex biogenesis protein BtpA-like protein AlphaFold + ColabFold – – 0.233 No Hit 0.0% —
4962 KP13_02188 hypothetical protein AlphaFold + ColabFold –
GO:1901135The chemical reactions and pathways involving carbohydrate derivative. GO:0097367Binding to a carbohydrate derivative. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. +25 total
0.233 No Hit 0.0% —
4963 KP13_02041 Aldo/keto reductase domain-containing protein AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
0.233 Hit 38.0% 3.75e-17
4964 KP13_00998 hypothetical protein AlphaFold + ColabFold
3.1.3.89
GO:0002953Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0046872Binding to a metal ion. +14 total
0.233 No Hit 0.0% —
4965 KP13_00948 Regulatory protein ada ada AlphaFold + ColabFold –
GO:0008270Binding to a zinc ion (Zn). GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. +811 total
0.233 Hit 30.7% 3.70e-15
4966 KP13_05340 hypothetical protein AlphaFold + ColabFold – – 0.232 No Hit 0.0% —
4967 KP13_03523 putative ribose/galactose/methyl galactoside import ATP-binding protein AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
0.232 Hit 40.8% 6.34e-06
4968 KP13_01965 Carbamoyl-phosphate synthase small chain carA AlphaFold + ColabFold
6.3.5.5
GO:0004088Catalysis of the reaction: hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H+. GO:0006207The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors. GO:0006541The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. +47 total
0.232 Hit 38.7% 1.32e-68
4969 KP13_00049 DNA polymerase III subunit beta dnaN AlphaFold + ColabFold –
GO:0009360The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. GO:0006260The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. GO:0003887Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. +58 total
0.232 No Hit 0.0% —
4970 KP13_04424 OriC-binding nucleoid-associated protein cnu AlphaFold + ColabFold – – 0.231 No Hit 0.0% —
4971 KP13_02766 putative GST-like protein AlphaFold + ColabFold – – 0.231 No Hit 0.0% —
4972 KP13_01862 putative ABC transporter ATP-binding protein AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
0.231 Hit 39.2% 6.48e-34
4973 KP13_00111 oxaloacetate decarboxylase AlphaFold + ColabFold
4.1.3.17
GO:0047443Catalysis of the reactions: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate, and 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = oxaloacetate + pyruvate. GO:0046872Binding to a metal ion. GO:0042537The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives. +25 total
0.231 No Hit 0.0% —
4974 KP13_31881 hypothetical protein AlphaFold + ColabFold – – 0.23 No Hit 0.0% —
4975 KP13_03058 putative Type VI secretion system protein AlphaFold + ColabFold – – 0.23 No Hit 0.0% —
Page of 234 · 5842 total proteins