Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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5572 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
401 PA4476 hypothetical protein PA4476 AlphaFold –
GO:0015914The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
0.932 No Hit N/A —
402 PA4114 spermidine acetyltransferase PA4114 AlphaFold –
GO:0008080Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.932 No Hit N/A —
403 PA4076 hypothetical protein PA4076 AlphaFold – – 0.932 No Hit N/A —
404 PA3786 hypothetical protein PA3786 AlphaFold – – 0.932 No Hit N/A —
405 PA3238 hypothetical protein PA3238 AlphaFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
0.932 No Hit N/A —
406 PA3030 molybdenum cofactor guanylyltransferase PA3030, mobA AlphaFold
2.7.7.77
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005525Binding to GTP, guanosine triphosphate. GO:0046872Binding to a metal ion. +58 total
0.932 No Hit N/A —
407 PA2914 ABC transporter permease PA2914 AlphaFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0033214A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores is imported into the cell by transmembrane transport or endocytosis. +14 total
0.932 No Hit N/A —
408 PA5194 hypothetical protein PA5194 AlphaFold – – 0.931 No Hit N/A —
409 PA4974 hypothetical protein PA4974 AlphaFold –
GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:1990281A protein complex that is capable of efflux transmembrane transporter activity. GO:0015562Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. +36 total
0.931 No Hit N/A —
410 PA4838 hypothetical protein PA4838 AlphaFold – – 0.931 No Hit N/A —
411 PA4340 hypothetical protein PA4340 AlphaFold – – 0.931 No Hit N/A —
412 PA4207 resistance-nodulation-cell division (RND) efflux transporter mexI, PA4207 AlphaFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0042910Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +25 total
0.931 No Hit N/A —
413 PA3731 hypothetical protein PA3731 AlphaFold – – 0.931 No Hit N/A —
414 PA3720 hypothetical protein PA3720 AlphaFold – – 0.931 No Hit N/A —
415 PA3605 hypothetical protein PA3605 AlphaFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
0.931 No Hit N/A —
416 PA2877 transcriptional regulator PA2877 AlphaFold –
GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. GO:0006351The synthesis of an RNA transcript from a DNA template. +14 total
0.931 No Hit N/A —
417 PA2538 hypothetical protein PA2538 AlphaFold – – 0.931 No Hit N/A —
418 PA1439 hypothetical protein PA1439 AlphaFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.931 No Hit N/A —
419 PA1319 cytochrome o ubiquinol oxidase subunit III PA1319, cyoC AlphaFold –
GO:0009319A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0009486Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space]. +69 total
0.931 Hit 27.0% 7.42e-10
420 PA0999 3-oxoacyl-ACP synthase PA0999, pqsD Experimental + AlphaFold
2.3.1.262
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0004315Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]. GO:0016746Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). +47 total
0.931 No Hit N/A —
421 PA0279 transcriptional regulator PA0279 AlphaFold –
GO:0097063Binding to and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++). GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +58 total
0.931 No Hit N/A —
422 PA3385 alginate and motility regulator Z PA3385, amrZ Experimental + AlphaFold –
GO:0032993A macromolecular complex containing both protein and DNA molecules. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0001217A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets. +1114 total
0.93 No Hit N/A —
423 PA2695 hypothetical protein PA2695 AlphaFold – – 0.93 No Hit N/A —
424 PA2274 hypothetical protein PA2274 AlphaFold – – 0.93 No Hit N/A —
425 PA1177 nitrate reductase protein NapE PA1177, napE AlphaFold – – 0.93 No Hit N/A —
Page of 223 · 5572 total proteins