Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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5572 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5376 PA0135 hypothetical protein PA0135 AlphaFold – – No pocket No Hit N/A —
5377 PA0567 hypothetical protein PA0567 AlphaFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No pocket No Hit N/A —
5378 PA5068 twin-arginine translocation protein TatA tatA, PA5068 AlphaFold –
GO:0033281A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins. GO:0008320Enables the transfer of a protein from one side of a membrane to the other. GO:0043953The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex. +25 total
No pocket No Hit N/A —
5379 PA5440a hypothetical protein ColabFold – – No pocket No Hit N/A —
5380 PA0719 hypothetical protein PA0719 AlphaFold – – No pocket No Hit N/A —
5381 PA3461 hypothetical protein PA3461 AlphaFold –
GO:0004177Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain. GO:0046872Binding to a metal ion. GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
No pocket No Hit N/A —
5382 PA2980 hypothetical protein PA2980 AlphaFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
No pocket Hit 51.0% 1.71e-11
5383 PA4294 hypothetical protein PA4294 AlphaFold – – No pocket No Hit N/A —
5384 PA1705 type III secretion regulator pcrG, PA1705 AlphaFold –
GO:0050709Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
No pocket No Hit N/A —
5385 PA0062 hypothetical protein PA0062 AlphaFold – – No pocket No Hit N/A —
5386 PA4635a hypothetical protein ColabFold – – No pocket No Hit N/A —
5387 PA3049 ribosome modulation factor PA3049, rmf AlphaFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0006417Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
No pocket No Hit N/A —
5388 PA4645 hypoxanthine-guanine phosphoribosyltransferase PA4645 AlphaFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0004422Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. GO:0000287Binding to a magnesium (Mg) ion. +47 total
No pocket Hit 26.3% 5.66e-13
5389 PA4077 transcriptional regulator PA4077 AlphaFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No pocket No Hit N/A —
5390 PA1112b hypothetical protein ColabFold – – No pocket No Hit N/A —
5391 PA1996 peptidyl-prolyl cis-trans isomerase C1 PA1996, ppiC1 AlphaFold
5.2.1.8
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0003755Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
No pocket Hit 35.4% 2.44e-09
5392 PA3140 hypothetical protein PA3140 AlphaFold –
GO:0015627A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0006281The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. +14 total
No pocket Hit 43.8% 7.46e-06
5393 PA0627 hypothetical protein XR2, PA0627 AlphaFold – – No pocket No Hit N/A —
5394 PA1536 hypothetical protein PA1536 AlphaFold – – No pocket No Hit N/A —
5395 PA1969 hypothetical protein PA1969 AlphaFold – – No pocket No Hit N/A —
5396 PA1675 hypothetical protein PA1675 AlphaFold –
GO:0004520Catalysis of the cleavage of ester linkages within deoxyribonucleic acid by creating internal breaks.
No pocket No Hit N/A —
5397 PA1471 hypothetical protein PA1471 AlphaFold – – No pocket No Hit N/A —
5398 PA0960 hypothetical protein slyX, PA0960 AlphaFold – – No pocket No Hit N/A —
5399 PA0922 hypothetical protein PA0922 AlphaFold – – No pocket No Hit N/A —
5400 PA4737 hypothetical protein ColabFold – – No pocket No Hit N/A —
Page of 223 · 5572 total proteins