Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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5572 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5326 PA0050 hypothetical protein PA0050 AlphaFold – – No pocket No Hit N/A —
5327 PA4364 hypothetical protein PA4364 AlphaFold – – No pocket No Hit N/A —
5328 PA0621 hypothetical protein PA0621 AlphaFold – – No pocket No Hit N/A —
5329 PA5494 hypothetical protein PA5494 AlphaFold – – No pocket No Hit N/A —
5330 PA3802 histidine--tRNA ligase PA3802, hisS AlphaFold
6.1.1.21
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0004821Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). +25 total
No pocket Hit 30.6% 5.24e-08
5331 PA1882 transporter PA1882 AlphaFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +25 total
No pocket No Hit N/A —
5332 PA4934 30S ribosomal protein S18 rpsR, PA4934 AlphaFold –
GO:0022627The small subunit of a ribosome located in the cytosol. GO:0070181Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA. GO:0003735The action of a molecule that contributes to the structural integrity of the ribosome. +25 total
No pocket Hit 40.7% 2.92e-06
5333 PA0648 hypothetical protein PA0648 AlphaFold – – No pocket No Hit N/A —
5334 PA2461 hypothetical protein PA2461 AlphaFold – – No pocket No Hit N/A —
5335 PA0531 glutamine amidotransferase PA0531 AlphaFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
No pocket No Hit N/A —
5336 PA0788a hypothetical protein ColabFold – – No pocket No Hit N/A —
5337 PA3669 hypothetical protein PA3669 AlphaFold – – No pocket No Hit N/A —
5338 PA3289 hypothetical protein PA3289 AlphaFold – – No pocket No Hit N/A —
5339 PA4312 hypothetical protein PA4312 AlphaFold –
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
No pocket No Hit N/A —
5340 PA2445 glycine dehydrogenase gcvP2 UnavailableNo structure available — sequence may exceed the prediction length limit –
GO:0006546The chemical reactions and pathways resulting in the breakdown of glycine. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0006544The chemical reactions and pathways involving glycine, aminoethanoic acid. +14 total
No structure No structure No structure No structure
5341 PA2402 peptide synthase PA2402 UnavailableNo structure available — sequence may exceed the prediction length limit –
GO:0016874Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. GO:0031177Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate). GO:0072330The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. +25 total
No structure No structure No structure No structure
5342 PA3161 integration host factor subunit beta himD, ihfB, PA3161 AlphaFold –
GO:0005694A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +47 total
No pocket No Hit N/A —
5343 PA5306 hypothetical protein PA5306 AlphaFold – – No pocket No Hit N/A —
5344 PA3847 hypothetical protein PA3847 AlphaFold – – No pocket No Hit N/A —
5345 PA0954 acylphosphatase PA0954, acyP AlphaFold
3.6.1.7
GO:0003998Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.
No pocket Hit 42.9% 1.10e-06
5346 PA1105 flagellar biosynthesis chaperone fliJ, PA1105 AlphaFold –
GO:0009288A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0003774Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force). +58 total
No pocket No Hit N/A —
5347 PA1123 hypothetical protein PA1123 AlphaFold – – No pocket No Hit N/A —
5348 PA1189 Zn-dependent metalloprotease PA1189, sprT AlphaFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0008270Binding to a zinc ion (Zn). GO:0006950Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
No pocket No Hit N/A —
5349 PA5123 hypothetical protein PA5123 AlphaFold – – No pocket No Hit N/A —
5350 PA2424 peptide synthase pvdL, PA2424 UnavailableNo structure available — sequence may exceed the prediction length limit –
GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0016874Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. GO:0031177Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate). +811 total
No structure No structure No structure No structure
Page of 223 · 5572 total proteins