Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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5572 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5401 PA0160 hypothetical protein PA0160 AlphaFold – – No pocket No Hit N/A —
5402 PA2894 hypothetical protein PA2894 AlphaFold – – No pocket No Hit N/A —
5403 PA0874 hypothetical protein PA0874 AlphaFold – – No pocket No Hit N/A —
5404 PA4791 hypothetical protein PA4791 AlphaFold – – No pocket No Hit N/A —
5405 PA3791 hypothetical protein PA3791 AlphaFold – – No pocket No Hit N/A —
5406 PA1034 hypothetical protein PA1034 AlphaFold – – No pocket No Hit N/A —
5407 PA0941 hypothetical protein PA0941 AlphaFold – – No pocket No Hit N/A —
5408 PA4530 zinc-binding protein yacG, PA4530 AlphaFold –
GO:0008657Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. GO:0008270Binding to a zinc ion (Zn). GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
No pocket No Hit N/A —
5409 PA2694 thioredoxin PA2694 AlphaFold – – No pocket Hit 43.1% 9.31e-07
5410 PA3741 acyl-CoA thioesterase PA3741 AlphaFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0052816Catalysis of the reaction: a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H+. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. +36 total
No pocket Hit 34.1% 1.35e-08
5411 PA4763 DNA repair protein RecN PA4763, recN AlphaFold –
GO:0043590The region of a bacterial cell to which the DNA is confined. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. +25 total
No pocket No Hit N/A —
5412 PA3260 transcriptional regulator PA3260 AlphaFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No pocket No Hit N/A —
5413 PA2486 hypothetical protein PA2486 AlphaFold – – No pocket No Hit N/A —
5414 PA0818 hypothetical protein PA0818 AlphaFold – – No pocket No Hit N/A —
5415 PA0645 hypothetical protein PA0645 AlphaFold – – No pocket No Hit N/A —
5416 PA3634 cell division protein FtsB PA3634, ftsB AlphaFold –
GO:0032153The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles. GO:0030428A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
No pocket No Hit N/A —
5417 PA2746a hypothetical protein ColabFold – – No pocket No Hit N/A —
5418 PA3674 hypothetical protein PA3674 AlphaFold – – No pocket No Hit N/A —
5419 PA1289 hypothetical protein PA1289 AlphaFold – – No pocket No Hit N/A —
5420 PA4468 superoxide dismutase sodM ColabFold –
GO:0004784Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + H2O2. GO:0046872Binding to a metal ion. GO:0006801The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
No pocket Hit 66.7% 7.27e-13
5421 PA2453 hypothetical protein PA2453 AlphaFold – – No pocket No Hit N/A —
5422 PA3990 hypothetical protein PA3990 AlphaFold –
GO:0072344A process of cytosolic translational elongation that takes place when a cytosolic ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.
No pocket No Hit N/A —
5423 PA0048 transcriptional regulator PA0048 AlphaFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No pocket No Hit N/A —
5424 PA5570 50S ribosomal protein L34 PA5570, rpmH AlphaFold –
GO:1990904A macromolecular complex that contains both RNA and protein molecules. GO:0005840An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. GO:0003735The action of a molecule that contributes to the structural integrity of the ribosome. +14 total
No pocket No Hit N/A —
5425 PA3722 hypothetical protein PA3722 AlphaFold – – No pocket No Hit N/A —
Page of 223 · 5572 total proteins