Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
5842 / 5842 proteins
No filters or custom sorting applied — click to see defaults

Scoring formula None

Sorted by Druggability (P2Rank preferred) (descending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5276 KP13_04752 HPP family protein AlphaFold DB model + ColabFold model – – No map 0.045 0.221 No Hit 0.0% —
5277 KP13_04037 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.045 0.41 No Hit 0.0% —
5278 KP13_03282 hypothetical protein ColabFold model – – No map 0.045 0.653 No Hit 0.0% —
5279 KP13_01932 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.045 No Hit 0.0% —
5280 KP13_01529 ABC-type high-affinity branched-chain amino acid transport system livJ AlphaFold DB model + ColabFold model –
GO:0006865The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
No map 0.045 0.348 No Hit 0.0% —
5281 KP13_31789 DUF336 family protein AlphaFold DB model + ColabFold model – – No map 0.044 0.538 No Hit 0.0% —
5282 KP13_05810 hypothetical protein ColabFold model – – No map 0.044 0.821 No Hit 0.0% —
5283 KP13_03020 Histidine utilization repressor hutC AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0045892Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +25 total
No map 0.044 0.528 No Hit 0.0% —
5284 KP13_02794 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.044 0.15 No Hit 0.0% —
5285 KP13_02376 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0044010A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
No map 0.044 0.46 No Hit 0.0% —
5286 KP13_02307 Propanediol utilization B12-related protein AlphaFold DB model + ColabFold model –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0008817Catalysis of the reaction: 2 ATP + 2 corrinoid + reduced [electron-transfer flavoprotein] = 2 adenosylcorrinoid + 3 H+ + oxidized [electron-transfer flavoprotein] + 2 triphosphate. The corrinoid can be cob(II)yrinate a,c diamide, cob(II)inamide or cob(II)alamin.
No map 0.044 0.658 Hit 45.2% 2.05e-11
5287 KP13_01780 D-methionine transport system permease protein metI metI AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
No map 0.044 0.655 No Hit 0.0% —
5288 KP13_01753 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.044 0.666 No Hit 0.0% —
5289 KP13_00902 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.044 0.221 No Hit 0.0% —
5290 KP13_00580 Regulator of ribonuclease activity A rraA AlphaFold DB model + ColabFold model –
GO:0008428Binds to and stops, prevents or reduces the activity of ribonuclease. GO:0051252Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
No map 0.044 0.096 No Hit 0.0% —
5291 KP13_00393 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.044 0.312 No Hit 0.0% —
5292 KP13_05063 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.043 0.547 No Hit 0.0% —
5293 KP13_03512 Secretion protein HlyD family AlphaFold DB model + ColabFold model – – No map 0.043 0.882 No Hit 0.0% —
5294 KP13_01734 Sec-independent protein translocase protein tatA tatA AlphaFold DB model + ColabFold model –
GO:0015031The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0043953The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex. +36 total
No map N/A 0.043 No Hit 0.0% —
5295 KP13_00636 Molybdopterin-guanine dinucleotide biosynthesis protein B mobB AlphaFold DB model + ColabFold model –
GO:0005525Binding to GTP, guanosine triphosphate. GO:0006777The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
No map 0.043 0.437 No Hit 0.0% —
5296 KP13_31877 hypothetical protein Experimental + ColabFold model – – No map 0.042 0.634 No Hit 0.0% —
5297 KP13_14302 30S ribosomal protein S20 AlphaFold DB model + ColabFold model –
GO:0003723Binding to an RNA molecule or a portion thereof. GO:0006412The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. GO:0005840An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. +47 total
No map 0.042 0.091 No Hit 0.0% —
5298 KP13_05100 putative endoribonuclease AlphaFold DB model + ColabFold model –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0019239Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH4+/NH2R).
No map 0.042 0.483 No Hit 0.0% —
5299 KP13_02745 putative Fe(2+)-trafficking protein AlphaFold DB model + ColabFold model –
GO:0005506Binding to an iron (Fe) ion. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0034599Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
No map 0.042 0.836 No Hit 0.0% —
5300 KP13_02244 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.042 0.823 No Hit 0.0% —
Page of 234 · 5842 total proteins