Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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Rows
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5726 KP13_01062 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.035 No Hit 0.0% —
5727 KP13_00900 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.035 No Hit 0.0% —
5728 KP13_00486 Divalent-cation tolerance protein cutA cutA AlphaFold DB model + ColabFold model –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005507Binding to a copper (Cu) ion. GO:0010038Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
No map 0.035 Hit 40.5% 8.45e-16
5729 KP13_00430 putative adhesin AlphaFold DB model + ColabFold model –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
No map 0.035 No Hit 0.0% —
5730 KP13_03548 Pyridoxine kinase pdxK AlphaFold DB model + ColabFold model
2.7.1.35
GO:0009443Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis. GO:0008478Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
No map 0.034 Hit 29.5% 5.80e-22
5731 KP13_03431 GCN5-related N-acetyltransferase (GNAT) domain-containing protein AlphaFold DB model + ColabFold model –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
No map 0.034 No Hit 0.0% —
5732 KP13_00572 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.034 No Hit 0.0% —
5733 KP13_01702 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.033 No Hit 0.0% —
5734 KP13_04607 4-hydroxy-2-oxovalerate aldolase mhpE AlphaFold DB model + ColabFold model
4.1.3.39
GO:0019439OBSOLETE. The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring. GO:0016833Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. +58 total
No map 0.032 Hit 26.5% 5.31e-07
5735 KP13_01397 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.032 No Hit 0.0% —
5736 KP13_00829 Flavohemoprotein hmp AlphaFold DB model + ColabFold model
1.14.12.17
GO:0008941Catalysis of the reaction: 2 NO + 2 O2 + NAD(P)H + H+ = 2 nitrate + NAD(P)+. GO:0051409Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. +811 total
No map 0.032 Hit 26.0% 1.34e-08
5737 KP13_02226 Protein fimF fimF AlphaFold DB model + ColabFold model –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
No map 0.031 No Hit 0.0% —
5738 KP13_04770 Signal transduction protein pmrD pmrD AlphaFold DB model + ColabFold model – – No map 0.03 No Hit 0.0% —
5739 KP13_01424 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.03 No Hit 0.0% —
5740 KP13_01410 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.03 No Hit 0.0% —
5741 KP13_01364 PEP-sugar phosphotransferase enzyme IIB subunit AlphaFold DB model + ColabFold model
2.7.1.205 2.7.1.- 2.7.1.191 +14 total
GO:0009401The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC. GO:0008982Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
No map 0.03 No Hit 0.0% —
5742 KP13_00781 Peptide deformylase def AlphaFold DB model + ColabFold model –
GO:0042586Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.
No map 0.03 Hit 32.3% 2.95e-17
5743 KP13_32004 biofilm-dependent modulation domain-containing protein AlphaFold DB model + ColabFold model –
GO:0071468Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
No map 0.029 No Hit 0.0% —
5744 KP13_04566 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.029 No Hit 0.0% —
5745 KP13_31876 hypothetical protein ColabFold model – – No map 0.028 No Hit 0.0% —
5746 KP13_02193 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.027 No Hit 0.0% —
5747 KP13_01348 UDP-N-acetylenolpyruvoylglucosamine reductase murB AlphaFold DB model + ColabFold model
1.3.1.98
GO:0071949Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0050660Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. GO:0008762Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+. +58 total
No map 0.027 No Hit 0.0% —
5748 KP13_32400 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.026 No Hit 0.0% —
5749 KP13_31889 Cold shock-like protein CspE cspE AlphaFold DB model + ColabFold model –
GO:0003676Binding to a nucleic acid. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
No map 0.026 Hit 60.0% 6.40e-07
5750 KP13_04576 hypothetical protein ColabFold model – – No map 0.025 No Hit 0.0% —
Page of 234 · 5842 total proteins