Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5676 KP13_05556 LysM domain/BON superfamily protein AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
0.055 No Hit 0.0% —
5677 KP13_05416 hypothetical protein AlphaFold + ColabFold – – 0.055 No Hit 0.0% —
5678 KP13_03537 Acetyltransferase AlphaFold + ColabFold
2.3.1.-
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.055 Hit 35.5% 1.57e-07
5679 KP13_02764 hypothetical protein AlphaFold + ColabFold – – 0.055 No Hit 0.0% —
5680 KP13_02645 putative ferredoxin-like protein AlphaFold + ColabFold –
GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0051536Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.
0.055 No Hit 0.0% —
5681 KP13_02682 hypothetical protein AlphaFold + ColabFold – – 0.054 No Hit 0.0% —
5682 KP13_01394 Protein pemK pemK AlphaFold + ColabFold
3.1.-.-
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0004521Catalysis of the cleavage of ester linkages within ribonucleic acid by creating internal breaks. +25 total
0.053 No Hit 0.0% —
5683 KP13_06638 hypothetical protein AlphaFold + ColabFold – – 0.051 No Hit 0.0% —
5684 KP13_05143 Superoxide dismutase Fe sodB AlphaFold + ColabFold
1.15.1.1
GO:0004784Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + H2O2. GO:0006801The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. GO:0046872Binding to a metal ion. +25 total
0.051 Hit 58.3% 2.27e-07
5685 KP13_00262 hypothetical protein AlphaFold + ColabFold – – 0.051 No Hit 0.0% —
5686 KP13_05567 Aldo/keto reductase family AlphaFold + ColabFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
0.05 Hit 37.3% 6.21e-06
5687 KP13_00201 ADP-heptose--LPS heptosyltransferase 2 rfaF AlphaFold + ColabFold
2.4.99.24
GO:0009103The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. GO:0016757Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.05 No Hit 0.0% —
5688 KP13_05185 hypothetical protein AlphaFold + ColabFold – – 0.049 No Hit 0.0% —
5689 KP13_04060 putative transposase ColabFold –
GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.049 No Hit 0.0% —
5690 KP13_02850 PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM dhaM AlphaFold + ColabFold
2.7.1.121
GO:0047324Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate. GO:0016310The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. GO:0016772Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). +36 total
0.049 No Hit 0.0% —
5691 KP13_05297 hypothetical protein AlphaFold + ColabFold – – 0.048 No Hit 0.0% —
5692 KP13_04798 putative MobC mobilization protein ColabFold – – 0.048 No Hit 0.0% —
5693 KP13_04485 cytochrome cd1-nitrite reductase-like protein AlphaFold + ColabFold –
GO:0005515Binding to a protein.
0.048 No Hit 0.0% —
5694 KP13_02198 Peptide chain release factor 2 prfB AlphaFold + ColabFold –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0003747Involved in catalyzing the release of a nascent polypeptide chain from a ribosome. GO:0006415The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). +14 total
0.048 Hit 49.2% 7.54e-36
5695 KP13_02154 putative fimbrial protein AlphaFold + ColabFold –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
0.048 No Hit 0.0% —
5696 KP13_01790 Protein rof rof AlphaFold + ColabFold – – 0.048 No Hit 0.0% —
5697 KP13_00817 Holo-[acyl-carrier-protein] synthase acpS AlphaFold + ColabFold
2.7.8.7
GO:0008897Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. GO:0000287Binding to a magnesium (Mg) ion. GO:0006633The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. +14 total
0.047 No Hit 0.0% —
5698 KP13_02978 hypothetical protein AlphaFold + ColabFold – – 0.046 No Hit 0.0% —
5699 KP13_03319 (Dimethylallyl)adenosine tRNA methylthiotransferase miaB miaB AlphaFold + ColabFold
2.8.4.3
GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0035596Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor. GO:0016740Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. +69 total
0.045 Hit 35.8% 2.39e-86
5700 KP13_02252 Oligogalacturonate lyase AlphaFold + ColabFold –
GO:0045490The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. GO:0005515Binding to a protein. GO:0047487Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.
0.045 No Hit 0.0% —
Page of 234 · 5842 total proteins