Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3601 KP13_03485 WD40/YVTN repeat-like domain-containing protein AlphaFold DB model + ColabFold model –
GO:0005515Binding to a protein.
No map 0.212 No Hit 0.0% —
3602 KP13_03486 hypothetical protein ColabFold model – – No map 0.262 No Hit 0.0% —
3603 KP13_03488 putative oxidoreductase protein AlphaFold DB model + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
No map 0.982 No Hit 0.0% —
3604 KP13_03489 putative dTDP (deoxythimodone diphosphates)-4-dehydrorhamnose 3,5-epimerase, RmlC AlphaFold DB model + ColabFold model – – No map 0.905 No Hit 0.0% —
3605 KP13_03492 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.826 No Hit 0.0% —
3606 KP13_03493 Helix-turn-helix type 3 domain-containing protein AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0001046Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
No map 0.725 No Hit 0.0% —
3607 KP13_03494 Toxin-antitoxin system, toxin component, HigB family protein AlphaFold DB model + ColabFold model
3.1.-.-
GO:0090305OBSOLETE. The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis. GO:0110001A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon. GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks. +25 total
No map 0.298 No Hit 0.0% —
3608 KP13_03496 putative MFS general substrate transporter AlphaFold DB model + ColabFold model –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
No map 0.919 No Hit 0.0% —
3609 KP13_03497 Monoamine regulon transcriptional regulator moaR AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.923 No Hit 0.0% —
3610 KP13_03498 Anaerobic sulfatase-maturating enzyme atsB AlphaFold DB model + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. +25 total
No map 0.347 No Hit 0.0% —
3611 KP13_03501 Protein moaF moaF AlphaFold DB model + ColabFold model – – No map 0.371 No Hit 0.0% —
3612 KP13_03502 hypothetical protein ColabFold model – – No map 0.519 No Hit 0.0% —
3613 KP13_03504 putative extracellular solute-binding protein AlphaFold DB model + ColabFold model –
GO:0071705The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
No map 0.295 No Hit 0.0% —
3614 KP13_03505 Hippurate hydrolase hipO AlphaFold DB model + ColabFold model –
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0046872Binding to a metal ion. GO:0050118Catalysis of the reaction: H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + acetate. +14 total
No map 0.402 No Hit 0.0% —
3615 KP13_03506 hypothetical protein ColabFold model – – No map 0.434 No Hit 0.0% —
3616 KP13_03507 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.312 No Hit 0.0% —
3617 KP13_03508 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.747 No Hit 0.0% —
3618 KP13_03509 putative periplasmic binding protein AlphaFold DB model + ColabFold model – – No map 0.457 No Hit 0.0% —
3619 KP13_03510 putative ABC transporter permease protein AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
No map 0.746 No Hit 0.0% —
3620 KP13_03512 Secretion protein HlyD family AlphaFold DB model + ColabFold model – – No map 0.882 No Hit 0.0% —
3621 KP13_03513 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.671 No Hit 0.0% —
3622 KP13_03514 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.983 No Hit 0.0% —
3623 KP13_03516 Sucrose porin scrY AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0034219The process in which a carbohydrate is transported across a membrane. GO:0015288Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. +58 total
No map 0.912 No Hit 0.0% —
3624 KP13_03519 Sucrose-6-phosphate hydrolase scrB AlphaFold DB model + ColabFold model –
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. +14 total
No map 0.881 No Hit 0.0% —
3625 KP13_03520 Sucrose operon repressor scrR AlphaFold DB model + ColabFold model –
GO:0009750Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +36 total
No map 0.935 No Hit 0.0% —
Page of 234 · 5842 total proteins