Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
5842 / 5842 proteins
No filters or custom sorting applied — click to see defaults

Scoring formula None

Sorted by Druggability (P2Rank preferred) (descending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5076 KP13_04007 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.075 0.228 No Hit 0.0% —
5077 KP13_01135 LuxR transcriptional regulator AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.075 0.656 No Hit 0.0% —
5078 KP13_31865 Arabinose 5-phosphate isomerase GutQ gutQ AlphaFold DB model + ColabFold model
5.3.1.13
GO:0016853Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:1901135The chemical reactions and pathways involving carbohydrate derivative. +58 total
No map 0.074 0.346 No Hit 0.0% —
5079 KP13_31737 HTH-type transcriptional regulator dsdC AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. +14 total
No map 0.074 0.4 No Hit 0.0% —
5080 KP13_05324 putative glyoxalase family protein AlphaFold DB model + ColabFold model –
GO:0016853Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
No map 0.074 0.036 No Hit 0.0% —
5081 KP13_04350 PaaR repeat-containing lipoprotein AlphaFold DB model + ColabFold model – – No map 0.074 No pocket No Hit 0.0% —
5082 KP13_03785 hypothetical protein ColabFold model – – No map 0.074 0.382 No Hit 0.0% —
5083 KP13_03284 Endonuclease 8 bifunctional protein nei AlphaFold DB model + ColabFold model
3.2.2.- 4.2.99.18
GO:0008270Binding to a zinc ion (Zn). GO:0003684Binding to damaged DNA. GO:0003906Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). +811 total
No map 0.074 0.243 Hit 32.8% 3.75e-07
5084 KP13_01406 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.074 0.34 No Hit 0.0% —
5085 KP13_32174 PRD domain-containing protein ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
No map 0.073 0.763 No Hit 0.0% —
5086 KP13_05586 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.073 No Hit 0.0% —
5087 KP13_04944 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.073 0.195 No Hit 0.0% —
5088 KP13_03425 putative mechanosensitive ion channel AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0008381Enables the transmembrane transfer of an monoatomic ion by a channel that opens in response to a mechanical stress. +25 total
No map 0.073 0.91 No Hit 0.0% —
5089 KP13_01497 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.073 0.4 No Hit 0.0% —
5090 KP13_01474 Periplasmic binding protein AlphaFold DB model + ColabFold model –
GO:0030313An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present. GO:0030246Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
No map 0.073 0.264 No Hit 0.0% —
5091 KP13_01021 Colicin V production protein cvpA AlphaFold DB model + ColabFold model –
GO:0009403The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.073 0.608 No Hit 0.0% —
5092 KP13_00134 NUDIX hydrolase protein AlphaFold DB model + ColabFold model –
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0006753The chemical reactions and pathways involving any phosphorylated nucleoside. +14 total
No map 0.073 0.172 No Hit 0.0% —
5093 KP13_00114 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.073 No Hit 0.0% —
5094 KP13_05287 hypothetical protein ColabFold model – – No map N/A 0.072 No Hit 0.0% —
5095 KP13_04149 Tellurium resistance protein terE terE AlphaFold DB model + ColabFold model –
GO:0046690Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.
No map 0.072 0.322 No Hit 0.0% —
5096 KP13_03953 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.072 0.849 No Hit 0.0% —
5097 KP13_03889 putative diguanylate phosphodiesterase AlphaFold DB model + ColabFold model –
GO:0071111Catalysis of the reaction: cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H+.
No map 0.072 0.511 No Hit 0.0% —
5098 KP13_03832 thioredoxin domain-containing protein AlphaFold DB model + ColabFold model – – No map 0.072 0.295 No Hit 0.0% —
5099 KP13_01326 putative sn-glycerol-3-phosphate transport system permease protein AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.072 0.881 No Hit 0.0% —
5100 KP13_01315 putative HTH-type transcriptional regulator AlphaFold DB model + ColabFold model –
GO:1901135The chemical reactions and pathways involving carbohydrate derivative. GO:0097367Binding to a carbohydrate derivative. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. +25 total
No map 0.072 0.62 No Hit 0.0% —
Page of 234 · 5842 total proteins