Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1476 KP13_01137 CinA family protein Experimental + ColabFold – – 0.781 No Hit 0.0% —
1477 KP13_00743 Elongation factor Tu tufA AlphaFold + ColabFold –
GO:0003924Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. GO:0003746Functions in chain elongation during polypeptide synthesis at the ribosome. GO:0005525Binding to GTP, guanosine triphosphate. +14 total
0.781 Hit 81.2% 1.64e-09
1478 KP13_32205 multidrug resistance protein mdtL AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.78 No Hit 0.0% —
1479 KP13_31966 hypothetical protein ColabFold – – 0.78 No Hit 0.0% —
1480 KP13_31839 hypothetical protein AlphaFold + ColabFold – – 0.78 No Hit 0.0% —
1481 KP13_13130 Lipopolysaccharide biosynthesis protein wzzE wzzE AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0009103The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. GO:0009246The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria. +25 total
0.78 No Hit 0.0% —
1482 KP13_08843 LrgA family protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.78 No Hit 0.0% —
1483 KP13_05096 putative ABC transporter, ATP-binding protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.78 No Hit 0.0% —
1484 KP13_03814 6-phospho-beta-glucosidase bglA AlphaFold + ColabFold
3.2.1.86
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.78 Hit 30.0% 7.30e-47
1485 KP13_02689 hypothetical protein AlphaFold + ColabFold – – 0.78 No Hit 0.0% —
1486 KP13_00428 Fimbrial biogenesis outer membrane usher protein AlphaFold + ColabFold –
GO:0005515Binding to a protein. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015473A porin that acts in the assembly of fimbria together with fimbrial chaperone. +25 total
0.779 No Hit 0.0% —
1487 KP13_06662 hypothetical protein AlphaFold + ColabFold – – 0.778 No Hit 0.0% —
1488 KP13_05539 putative exporter protein, LysE family protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0006865The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.778 No Hit 0.0% —
1489 KP13_03353 Ribonuclease I rna AlphaFold + ColabFold –
GO:0003723Binding to an RNA molecule or a portion thereof. GO:0033897Catalysis of the reaction: a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H+. This reaction is a two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. GO:0006401The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
0.778 No Hit 0.0% —
1490 KP13_02527 Phenolic acid decarboxylase subunit C AlphaFold + ColabFold
4.1.1.-
GO:0016831Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0008694Catalysis of the reaction: a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + H+ = a 2-(all-trans-polyprenyl)phenol + CO2. +36 total
0.778 No Hit 0.0% —
1491 KP13_00617 D-tyrosyl-tRNA(Tyr) deacylase dtd AlphaFold + ColabFold
3.1.1.96 3.1.1.-
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0051499Catalysis of the reaction: a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H+. Removal of a D-amino acid from a charged tRNA. GO:0002161The hydrolysis of an incorrectly aminoacylated tRNA. +58 total
0.778 Hit 37.4% 3.65e-24
1492 KP13_04278 Raffinose permease AlphaFold + ColabFold –
GO:0008643The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0005351Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in). +36 total
0.777 No Hit 0.0% —
1493 KP13_02710 putative deoxythimodone diphosphates-4-dehydrorhamnose 3,5-epimerase AlphaFold + ColabFold – – 0.777 No Hit 0.0% —
1494 KP13_02072 Branched-chain amino acid transport system 2 carrier protein brnQ AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015658Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings. GO:0015803The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings. +69 total
0.777 No Hit 0.0% —
1495 KP13_01882 hypothetical protein AlphaFold + ColabFold – – 0.777 No Hit 0.0% —
1496 KP13_05284 putative high-affinity branched-chain amino acid ABC transporter membrane protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +25 total
0.776 No Hit 0.0% —
1497 KP13_04735 hypothetical protein AlphaFold + ColabFold – – 0.776 No Hit 0.0% —
1498 KP13_04557 hypothetical protein AlphaFold + ColabFold – – 0.776 No Hit 0.0% —
1499 KP13_01405 hypothetical protein AlphaFold + ColabFold – – 0.776 No Hit 0.0% —
1500 KP13_03900 HTH-type transcriptional regulator puuR puuR AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
0.775 No Hit 0.0% —
Page of 234 · 5842 total proteins